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Page 1
Mapping the human genetic architecture of COVID-19.
COVID-19 Host Genetics Initiative. COVID-19 Host Genetics Initiative. Nature. 2021 Dec;600(7889):472-477. doi: 10.1038/s41586-021-03767-x. Epub 2021 Jul 8. Nature. 2021. PMID: 34237774 Free PMC article.
Protection against SARS-CoV-2 after Covid-19 Vaccination and Previous Infection.
Hall V, Foulkes S, Insalata F, Kirwan P, Saei A, Atti A, Wellington E, Khawam J, Munro K, Cole M, Tranquillini C, Taylor-Kerr A, Hettiarachchi N, Calbraith D, Sajedi N, Milligan I, Themistocleous Y, Corrigan D, Cromey L, Price L, Stewart S, de Lacy E, Norman C, Linley E, Otter AD, Semper A, Hewson J, D'Arcangelo S, Chand M, Brown CS, Brooks T, Islam J, Charlett A, Hopkins S; SIREN Study Group. Hall V, et al. N Engl J Med. 2022 Mar 31;386(13):1207-1220. doi: 10.1056/NEJMoa2118691. Epub 2022 Feb 16. N Engl J Med. 2022. PMID: 35172051 Free PMC article.
The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection.
Goldswain H, Dong X, Penrice-Randal R, Alruwaili M, Shawli GT, Prince T, Williamson MK, Raghwani J, Randle N, Jones B, Donovan-Banfield I, Salguero FJ, Tree JA, Hall Y, Hartley C, Erdmann M, Bazire J, Jearanaiwitayakul T, Semple MG, Openshaw PJM, Baillie JK; ISARIC4C Investigators; Emmett SR, Digard P, Matthews DA, Turtle L, Darby AC, Davidson AD, Carroll MW, Hiscox JA. Goldswain H, et al. Genome Biol. 2023 Mar 13;24(1):47. doi: 10.1186/s13059-023-02881-5. Genome Biol. 2023. PMID: 36915185 Free PMC article.
SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses.
Dejnirattisai W, Huo J, Zhou D, Zahradník J, Supasa P, Liu C, Duyvesteyn HME, Ginn HM, Mentzer AJ, Tuekprakhon A, Nutalai R, Wang B, Dijokaite A, Khan S, Avinoam O, Bahar M, Skelly D, Adele S, Johnson SA, Amini A, Ritter TG, Mason C, Dold C, Pan D, Assadi S, Bellass A, Omo-Dare N, Koeckerling D, Flaxman A, Jenkin D, Aley PK, Voysey M, Costa Clemens SA, Naveca FG, Nascimento V, Nascimento F, Fernandes da Costa C, Resende PC, Pauvolid-Correa A, Siqueira MM, Baillie V, Serafin N, Kwatra G, Da Silva K, Madhi SA, Nunes MC, Malik T, Openshaw PJM, Baillie JK, Semple MG, Townsend AR, Huang KA, Tan TK, Carroll MW, Klenerman P, Barnes E, Dunachie SJ, Constantinides B, Webster H, Crook D, Pollard AJ, Lambe T; OPTIC Consortium; ISARIC4C Consortium; Paterson NG, Williams MA, Hall DR, Fry EE, Mongkolsapaya J, Ren J, Schreiber G, Stuart DI, Screaton GR. Dejnirattisai W, et al. Cell. 2022 Feb 3;185(3):467-484.e15. doi: 10.1016/j.cell.2021.12.046. Epub 2022 Jan 4. Cell. 2022. PMID: 35081335 Free PMC article.
Antibiotic review kit for hospitals (ARK-Hospital): a stepped-wedge cluster-randomised controlled trial.
Llewelyn MJ, Budgell EP, Laskawiec-Szkonter M, Cross ELA, Alexander R, Bond S, Coles P, Conlon-Bingham G, Dymond S, Evans M, Fok R, Frost KJ, Garcia-Arias V, Glass S, Gormley C, Gray K, Hamson C, Harvey D, Hills T, Iyer S, Johnson A, Jones N, Kang P, Kiapi G, Mack D, Makanga C, Mawer D, McCullagh B, Mirfenderesky M, McEwen R, Nag S, Nagar A, Northfield J, O'Driscoll J, Pegden A, Porter R, Powell N, Price D, Sheridan E, Slatter M, Stewart B, Watson C, Weichert I, Sivyer K, Wordsworth S, Quaddy J, Santillo M, Krusche A, Roope LSJ, Mowbray F, Hand KS, Dobson M, Crook DW, Vaughan L, Hopkins S, Yardley L, Peto TEA, Walker AS. Llewelyn MJ, et al. Among authors: mirfenderesky m. Lancet Infect Dis. 2023 Feb;23(2):207-221. doi: 10.1016/S1473-3099(22)00508-4. Epub 2022 Oct 4. Lancet Infect Dis. 2023. PMID: 36206793 Free article. Clinical Trial.
SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway.
Willett BJ, Grove J, MacLean OA, Wilkie C, De Lorenzo G, Furnon W, Cantoni D, Scott S, Logan N, Ashraf S, Manali M, Szemiel A, Cowton V, Vink E, Harvey WT, Davis C, Asamaphan P, Smollett K, Tong L, Orton R, Hughes J, Holland P, Silva V, Pascall DJ, Puxty K, da Silva Filipe A, Yebra G, Shaaban S, Holden MTG, Pinto RM, Gunson R, Templeton K, Murcia PR, Patel AH, Klenerman P, Dunachie S; PITCH Consortium; COVID-19 Genomics UK (COG-UK) Consortium; Haughney J, Robertson DL, Palmarini M, Ray S, Thomson EC. Willett BJ, et al. Nat Microbiol. 2022 Aug;7(8):1161-1179. doi: 10.1038/s41564-022-01143-7. Epub 2022 Jul 7. Nat Microbiol. 2022. PMID: 35798890 Free PMC article.
Surge of lower respiratory tract group A streptococcal infections in England in winter 2022: epidemiology and clinical profile.
Wrenn K, Blomquist PB, Inzoungou-Massanga C, Olufon O, Guy RL, Hatziioanou D, Findlater L, Smith I, Mirfenderesky M, Luyt K, Williams T, Stoianova S, Dickinson M, Pietzsch M, Jarvis CI, Brown C, Lamagni T, Kumar D. Wrenn K, et al. Among authors: mirfenderesky m. Lancet. 2023 Nov;402 Suppl 1:S93. doi: 10.1016/S0140-6736(23)02095-0. Lancet. 2023. PMID: 37997140
Probable Vertical Transmission of SARS-CoV-2 Infection.
Demirjian A, Singh C, Tebruegge M, Herbert R, Draz N, Mirfenderesky M, Jones V, Hinstridge P, Seneviratne R, Myers R, Ellis J, Miah S, Meadows CI, Kenny J, Alonso A, Handforth J, Perkins S, Butler M, Blackburn F, Douthwaite S, Pillay D, Chand M, Zambon M. Demirjian A, et al. Among authors: mirfenderesky m. Pediatr Infect Dis J. 2020 Sep;39(9):e257-e260. doi: 10.1097/INF.0000000000002821. Pediatr Infect Dis J. 2020. PMID: 32658096
Genomic reconstruction of the SARS-CoV-2 epidemic in England.
Vöhringer HS, Sanderson T, Sinnott M, De Maio N, Nguyen T, Goater R, Schwach F, Harrison I, Hellewell J, Ariani CV, Gonçalves S, Jackson DK, Johnston I, Jung AW, Saint C, Sillitoe J, Suciu M, Goldman N, Panovska-Griffiths J; Wellcome Sanger Institute COVID-19 Surveillance Team; COVID-19 Genomics UK (COG-UK) Consortium*; Birney E, Volz E, Funk S, Kwiatkowski D, Chand M, Martincorena I, Barrett JC, Gerstung M. Vöhringer HS, et al. Nature. 2021 Dec;600(7889):506-511. doi: 10.1038/s41586-021-04069-y. Epub 2021 Oct 14. Nature. 2021. PMID: 34649268 Free PMC article.
48 results