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Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease.
Kikuchi K, Saigusa D, Kanemitsu Y, Matsumoto Y, Thanai P, Suzuki N, Mise K, Yamaguchi H, Nakamura T, Asaji K, Mukawa C, Tsukamoto H, Sato T, Oikawa Y, Iwasaki T, Oe Y, Tsukimi T, Fukuda NN, Ho HJ, Nanto-Hara F, Ogura J, Saito R, Nagao S, Ohsaki Y, Shimada S, Suzuki T, Toyohara T, Mishima E, Shima H, Akiyama Y, Akiyama Y, Ichijo M, Matsuhashi T, Matsuo A, Ogata Y, Yang CC, Suzuki C, Breeggemann MC, Heymann J, Shimizu M, Ogawa S, Takahashi N, Suzuki T, Owada Y, Kure S, Mano N, Soga T, Wada T, Kopp JB, Fukuda S, Hozawa A, Yamamoto M, Ito S, Wada J, Tomioka Y, Abe T. Kikuchi K, et al. Among authors: ichijo m. Nat Commun. 2019 Apr 23;10(1):1835. doi: 10.1038/s41467-019-09735-4. Nat Commun. 2019. PMID: 31015435 Free PMC article.
Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5.
Oikawa Y, Izumi R, Koide M, Hagiwara Y, Kanzaki M, Suzuki N, Kikuchi K, Matsuhashi T, Akiyama Y, Ichijo M, Watanabe S, Toyohara T, Suzuki T, Mishima E, Akiyama Y, Ogata Y, Suzuki C, Hayashi H, Kodama EN, Hayashi KI, Itoi E, Aoki M, Kure S, Abe T. Oikawa Y, et al. Among authors: ichijo m. PLoS One. 2020 Dec 2;15(12):e0231064. doi: 10.1371/journal.pone.0231064. eCollection 2020. PLoS One. 2020. PMID: 33264289 Free PMC article.
SGLT-1-specific inhibition ameliorates renal failure and alters the gut microbial community in mice with adenine-induced renal failure.
Ho HJ, Kikuchi K, Oikawa D, Watanabe S, Kanemitsu Y, Saigusa D, Kujirai R, Ikeda-Ohtsubo W, Ichijo M, Akiyama Y, Aoki Y, Mishima E, Ogata Y, Oikawa Y, Matsuhashi T, Toyohara T, Suzuki C, Suzuki T, Mano N, Kagawa Y, Owada Y, Katayama T, Nakayama T, Tomioka Y, Abe T. Ho HJ, et al. Among authors: ichijo m. Physiol Rep. 2021 Dec;9(24):e15092. doi: 10.14814/phy2.15092. Physiol Rep. 2021. PMID: 34921520 Free PMC article.