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Hetero-Multivalent Targeted Liposomal Drug Delivery to Treat Pseudomonas aeruginosa Infections.
Singla A, Simbassa SB, Chirra B, Gairola A, Southerland MR, Shah KN, Rose RE, Chen Q, Basharat A, Baeza J, Raina R, Chapman MJ, Hassan AM, Ivanov I, Sen A, Wu HJ, Cannon CL. Singla A, et al. Among authors: southerland mr. ACS Appl Mater Interfaces. 2022 Sep 14;14(36):40724-40737. doi: 10.1021/acsami.2c12943. Epub 2022 Aug 26. ACS Appl Mater Interfaces. 2022. PMID: 36018830 Free PMC article.
Synthesis, characterization, in vitro SAR study, and preliminary in vivo toxicity evaluation of naphthylmethyl substituted bis-imidazolium salts.
Southerland MR, DeBord MA, Johnson NA, Crabtree SR, Alexander NE, Stromyer ML, Wagers PO, Panzner MJ, Wesdemiotis C, Shriver LP, Tessier CA, Youngs WJ. Southerland MR, et al. Bioorg Med Chem. 2021 Jan 15;30:115893. doi: 10.1016/j.bmc.2020.115893. Epub 2020 Nov 28. Bioorg Med Chem. 2021. PMID: 33333447 Free PMC article.
Anti-tumor activity of lipophilic imidazolium salts on select NSCLC cell lines.
Wright BD, Deblock MC, Wagers PO, Duah E, Robishaw NK, Shelton KL, Southerland MR, DeBord MA, Kersten KM, McDonald LJ, Stiel JA, Panzner MJ, Tessier CA, Paruchuri S, Youngs WJ. Wright BD, et al. Among authors: southerland mr. Med Chem Res. 2015 Jul;24(7):2838-2861. doi: 10.1007/s00044-015-1330-z. Epub 2015 Feb 13. Med Chem Res. 2015. PMID: 26446298 Free PMC article.
Synthesis, characterization, in vitro SAR and in vivo evaluation of N,N'bisnaphthylmethyl 2-alkyl substituted imidazolium salts against NSCLC.
DeBord MA, Southerland MR, Wagers PO, Tiemann KM, Robishaw NK, Whiddon KT, Konopka MC, Tessier CA, Shriver LP, Paruchuri S, Hunstad DA, Panzner MJ, Youngs WJ. DeBord MA, et al. Among authors: southerland mr. Bioorg Med Chem Lett. 2017 Feb 15;27(4):764-775. doi: 10.1016/j.bmcl.2017.01.035. Epub 2017 Jan 16. Bioorg Med Chem Lett. 2017. PMID: 28126518 Free PMC article.
Synthesis, anti-proliferative activity, SAR study, and preliminary in vivo toxicity study of substituted N,N'-bis(arylmethyl)benzimidazolium salts against a panel of non-small cell lung cancer cell lines.
Shelton KL, DeBord MA, Wagers PO, Southerland MR, Williams TM, Robishaw NK, Shriver LP, Tessier CA, Panzner MJ, Youngs WJ. Shelton KL, et al. Among authors: southerland mr. Bioorg Med Chem. 2017 Jan 1;25(1):421-439. doi: 10.1016/j.bmc.2016.11.009. Epub 2016 Nov 5. Bioorg Med Chem. 2017. PMID: 27876249 Free PMC article.