Physical activity, fatigue and quality of life in breast cancer patients

Rev Assoc Med Bras (1992). 2016 Jan-Feb;62(1):38-44. doi: 10.1590/1806-9282.62.01.38.

Abstract

Objective: to evaluate the relationship between levels of physical activity, fatigue and quality of life (QOL) in women diagnosed with breast cancer.

Methods: 215 women between the ages of 40 and 65 years were recruited at a cancer clinic. Physical activity levels were assessed by using the International Physical Activity Questionnaire (IPAQ), fatigue levels by using the revised Piper scale, and QOL by means of EORTC QLQ-C30 and WHOQOL-Bref. Statistical analysis was performed using Minitab statistical software, version 16.

Results: the mean age of subjects was 52.66 years (SD=8.6); patients were mostly white (58.14%) and overweight (55.81%). Most women were fatigued (72.09%) while physically active women showed lower symptoms of fatigue (p<0.001). Mean scores for QOL were significantly lower among fatigued women (p<0.001). More active women scored higher on all scales of QOL (EORTC), especially for functional capacity (p<0.001), compared with the sedentary patients. A significant association was found between level of physical activity and overall QOL (WHOQOL-Bref) for all domains (p<0.001). Climacteric symptoms ranged from mild to strong and did not show any statistically significant results; however, the most active women had the fewest symptoms.

Conclusion: physical activity appears to positively influence fatigue and QOL in women diagnosed with breast cancer.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Breast Neoplasms / physiopathology*
  • Breast Neoplasms / therapy
  • Cross-Sectional Studies
  • Exercise / physiology*
  • Fatigue / physiopathology*
  • Female
  • Humans
  • Middle Aged
  • Motor Activity / physiology
  • Quality of Life*
  • Sedentary Behavior
  • Socioeconomic Factors
  • Statistics, Nonparametric
  • Surveys and Questionnaires
  • Time Factors