Functionalization of 3D Chitinous Skeletal Scaffolds of Sponge Origin Using Silver Nanoparticles and Their Antibacterial Properties

Tomasz Machałowski; Maria Czajka; Iaroslav Petrenko; Heike Meissner; Christian Schimpf; David Rafaja; Jerzy Ziętek; Beata Dzięgiel; Łukasz Adaszek; Alona Voronkina; Valentin Kovalchuk; Jakub Jaroszewicz; Andriy Fursov; Mehdi Rahimi-Nasrabadi; Dawid Stawski; Nicole Bechmann; Teofil Jesionowski; Hermann Ehrlich

doi:10.3390/md18060304

Functionalization of 3D Chitinous Skeletal Scaffolds of Sponge Origin Using Silver Nanoparticles and Their Antibacterial Properties

Mar Drugs. 2020 Jun 10;18(6):304. doi: 10.3390/md18060304.

Authors

Tomasz Machałowski^{1

2}, Maria Czajka³, Iaroslav Petrenko², Heike Meissner⁴, Christian Schimpf⁵, David Rafaja⁵, Jerzy Ziętek⁶, Beata Dzięgiel⁶, Łukasz Adaszek⁶, Alona Voronkina⁷, Valentin Kovalchuk⁸, Jakub Jaroszewicz⁹, Andriy Fursov², Mehdi Rahimi-Nasrabadi^{10

11}, Dawid Stawski³, Nicole Bechmann^{12

13

14

15}, Teofil Jesionowski¹, Hermann Ehrlich^{2

16}

Affiliations

¹ Institute of Chemical Technology and Engineering, Faculty of Chemical Technology, Poznan University of Technology, Berdychowo 4, 60965 Poznan, Poland.
² Institute of Electronics and Sensor Materials, TU Bergakademie Freiberg, Gustav-Zeuner str. 3, 09599 Freiberg, Germany.
³ Institute of Material Science of Textiles and Polymer Composites, Lodz University of Technology, Zeromskiego 16, 90924 Lodz, Poland.
⁴ Department of Prosthetic Dentistry, Faculty of Medicine and University Hospital Carl Gustav Carus of Technische Universität Dresden, Fetscherstraße 74, 01307 Dresden, Germany.
⁵ Institute of Materials Science, TU Bergakademie Freiberg, Gustav-Zeuner str. 5, 09599 Freiberg, Germany.
⁶ Department of Epizootiology and Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Sciences, Akademicka 13, 20612 Lublin, Poland.
⁷ Department of Pharmacy, National Pirogov Memorial Medical University, Pirogov str. 56, 21018 Vinnitsa, Ukraine.
⁸ Department of Microbiology, National Pirogov Memorial Medical University, Pirogov str. 56, 21018 Vinnitsa, Ukraine.
⁹ Materials Design Division, Faculty of Materials Science and Engineering, Warsaw University of Technology, Woloska 141, 02507 Warsaw, Poland.
¹⁰ Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran 1951683759, Iran.
¹¹ Faculty of Pharmacy, Baqiyatallah University of Medical Sciences, Tehran 1951683759, Iran.
¹² Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
¹³ Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
¹⁴ Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthur-Scheunert-Allee 114, 14558 Nuthetal, Germany.
¹⁵ German Center for Diabetes Research (DZD), Ingolstaedter Landstrasse 1, 85764 München-Neuherberg, Germany.
¹⁶ Center for Advanced Technology, Adam Mickiewicz University, Uniwersytetu Poznańskiego 10, 61614 Poznan, Poland.

Abstract

Chitin, as one of nature's most abundant structural polysaccharides, possesses worldwide, high industrial potential and a functionality that is topically pertinent. Nowadays, the metallization of naturally predesigned, 3D chitinous scaffolds originating from marine sponges is drawing focused attention. These invertebrates represent a unique, renewable source of specialized chitin due to their ability to grow under marine farming conditions. In this study, the development of composite material in the form of 3D chitin-based skeletal scaffolds covered with silver nanoparticles (AgNPs) and Ag-bromide is described for the first time. Additionally, the antibacterial properties of the obtained materials and their possible applications as a water filtration system are also investigated.

Keywords: 3D scaffolds; AgNPs; Aplysina aerophoba; antibacterial properties; chitin; sponges.

MeSH terms

Animals
Anti-Bacterial Agents / pharmacology*
Aquatic Organisms
Chitin / chemistry*
Escherichia coli / drug effects*
Metal Nanoparticles / chemistry
Porifera*
Silver / chemistry
Structure-Activity Relationship

Substances

Anti-Bacterial Agents
Chitin
Silver