Optoelectronic capillary sensors in microfluidic and point-of-care instrumentation

Sensors (Basel). 2010;10(4):3771-97. doi: 10.3390/s100403771. Epub 2010 Apr 14.

Abstract

This paper presents a review, based on the published literature and on the authors' own research, of the current state of the art of fiber-optic capillary sensors and related instrumentation as well as their applications, with special emphasis on point-of-care chemical and biochemical sensors, systematizing the various types of sensors from the point of view of the principles of their construction and operation. Unlike classical fiber-optic sensors which rely on changes in light propagation inside the fiber as affected by outside conditions, optical capillary sensors rely on changes of light transmission in capillaries filled with the analyzed liquid, which opens the possibility of interesting new applications, while raising specific issues relating to the construction, materials and instrumentation of those sensors.

Keywords: biochemical sensors; capillary sensors; chemical sensors; fiber-optic sensors; hollow-core sensors; liquid-core sensors; optical capillaries; optical fibers; optochemical sensors; photonic sensors.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biosensing Techniques / instrumentation
  • Biosensing Techniques / methods*
  • Capillaries / metabolism
  • Fiber Optic Technology / instrumentation*
  • Fiber Optic Technology / methods
  • Humans
  • Light
  • Microfluidics / instrumentation*
  • Optical Fibers*
  • Point-of-Care Systems*