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36th International Symposium on Intensive Care and Emergency Medicine : Brussels, Belgium. 15-18 March 2016.
Bateman RM, Sharpe MD, Jagger JE, Ellis CG, Solé-Violán J, López-Rodríguez M, Herrera-Ramos E, Ruíz-Hernández J, Borderías L, Horcajada J, González-Quevedo N, Rajas O, Briones M, Rodríguez de Castro F, Rodríguez Gallego C, Esen F, Orhun G, Ergin Ozcan P, Senturk E, Ugur Yilmaz C, Orhan N, Arican N, Kaya M, Kucukerden M, Giris M, Akcan U, Bilgic Gazioglu S, Tuzun E, Riff R, Naamani O, Douvdevani A, Takegawa R, Yoshida H, Hirose T, Yamamoto N, Hagiya H, Ojima M, Akeda Y, Tasaki O, Tomono K, Shimazu T, Ono S, Kubo T, Suda S, Ueno T, Ikeda T, Hirose T, Ogura H, Takahashi H, Ojima M, Kang J, Nakamura Y, Kojima T, Shimazu T, Ikeda T, Suda S, Izutani Y, Ueno T, Ono S, Taniguchi T, O M, Dinter C, Lotz J, Eilers B, Wissmann C, Lott R, Meili MM, Schuetz PS, Hawa H, Sharshir M, Aburageila M, Salahuddin N, Chantziara V, Georgiou S, Tsimogianni A, Alexandropoulos P, Vassi A, Lagiou F, Valta M, Micha G, Chinou E, Michaloudis G, Kodaira A, Ikeda T, Ono S, Ueno T, Suda S, Izutani Y, Imaizumi H, De la Torre-Prados MV, Garcia-De la Torre A, Enguix-Armada A, Puerto-Morlan A, Perez-Valero V, Garcia-Alcantara A, Bolton N, Dudziak J, Bonney S, Tridente A, Nee P, Nicolaes G, Wiewel M, Schultz M, Wildhag… See abstract for full author list ➔ Bateman RM, et al. Crit Care. 2016 Apr 20;20(Suppl 2):94. doi: 10.1186/s13054-016-1208-6. Crit Care. 2016. PMID: 27885969 Free PMC article.
C. Gruda, P. O'Sullivan, V. P. Dan, T. Guliashvili, A. Scheirer, T. D. Golobish, V. ...Bhandari P221 - Setting optimal flow rate during high flow nasal cannula support: preliminary results T. Mauri, C. Turrini, T. Langer, P. Taccon …
C. Gruda, P. O'Sullivan, V. P. Dan, T. Guliashvili, A. Scheirer, T. D. Golobish, V. ...Bhandari P221 - Setting o …
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, … See abstract for full author list ➔ Sims R, et al. Nat Genet. 2017 Sep;49(9):1373-1384. doi: 10.1038/ng.3916. Epub 2017 Jul 17. Nat Genet. 2017. PMID: 28714976 Free PMC article.

In stage 1, we genotyped 34,174 samples using a whole-exome microarray. In stage 2, we tested associated variants (P < 1 10(-4)) in 35,962 independent samples using de novo genotyping and imputed genotypes. In stage 3, we used an additional 14,997 samples to test the mo

…

In stage 1, we genotyped 34,174 samples using a whole-exome microarray. In stage 2, we tested associated variants (P < 1 10(-4)) i

…
Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries.
NIHR Global Health Unit on Global Surgery; COVIDSurg Collaborative. NIHR Global Health Unit on Global Surgery, et al. Lancet. 2022 Nov 5;400(10363):1607-1617. doi: 10.1016/S0140-6736(22)01846-3. Epub 2022 Oct 31. Lancet. 2022. PMID: 36328042 Free PMC article.
In the mixed-effects model, a 10-point increase in SPI corresponded to a 3.6% (95% CI 3.0-4.1; p<0.0001) increase in SVR. This was consistent in HIC (4.8% [4.1-5.5]; p<0.0001), MIC (2.8 [2.0-3.7]; p<0.0001), and LIC (3.8 [1.3-6.7%]; p<0.000 …
In the mixed-effects model, a 10-point increase in SPI corresponded to a 3.6% (95% CI 3.0-4.1; p<0.0001) increase in SVR. This was …
Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study.
COVIDSurg Collaborative; GlobalSurg Collaborative. COVIDSurg Collaborative, et al. Anaesthesia. 2021 Nov;76(11):1454-1464. doi: 10.1111/anae.15560. Epub 2021 Aug 9. Anaesthesia. 2021. PMID: 34371522 Free article. Clinical Trial.
Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95% …
Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0% …
Predictors of clinically significant quality of life impairment in Parkinson's disease.
Santos García D, de Deus Fonticoba T, Cores C, Muñoz G, Paz González JM, Martínez Miró C, Suárez E, Jesús S, Aguilar M, Pastor P, Planellas L, Cosgaya M, García Caldentey J, Caballol N, Legarda I, Hernández Vara J, Cabo I, López Manzanares L, González Aramburu I, Ávila Rivera MA, Catalán MJ, Nogueira V, Puente V, Ruíz de Arcos M, Borrué C, Solano Vila B, Álvarez Sauco M, Vela L, Escalante S, Cubo E, Carrillo Padilla F, Martínez Castrillo JC, Sánchez Alonso P, Alonso Losada MG, López Ariztegui N, Gastón I, Clavero P, Kulisevsky J, Blázquez Estrada M, Seijo M, Rúiz Martínez J, Valero C, Kurtis M, de Fábregues O, González Ardura J, Ordás C, López Díaz LM, McAfee D, Martinez-Martin P, Mir P; COPPADIS Study Group. Santos García D, et al. NPJ Parkinsons Dis. 2021 Dec 16;7(1):118. doi: 10.1038/s41531-021-00256-w. NPJ Parkinsons Dis. 2021. PMID: 34916528 Free PMC article.
A comparison with a control group was conducted for GQoL. GQoL did not change significantly in PD patients (N = 507; p = 0.686) or in the control group (N = 119; p = 0.192). The mean PDQ-39SI was significantly increased in PD patients (62.7 8.5 years old; 58.8% male …
A comparison with a control group was conducted for GQoL. GQoL did not change significantly in PD patients (N = 507; p = 0.686) or in …
Immune and spermatogenesis-related loci are involved in the development of extreme patterns of male infertility.
Cerván-Martín M, Tüttelmann F, Lopes AM, Bossini-Castillo L, Rivera-Egea R, Garrido N, Lujan S, Romeu G, Santos-Ribeiro S, Castilla JA, Carmen Gonzalvo M, Clavero A, Maldonado V, Vicente FJ, González-Muñoz S, Guzmán-Jiménez A, Burgos M, Jiménez R, Pacheco A, González C, Gómez S, Amorós D, Aguilar J, Quintana F, Calhaz-Jorge C, Aguiar A, Nunes J, Sousa S, Pereira I, Pinto MG, Correia S, Sánchez-Curbelo J, López-Rodrigo O, Martín J, Pereira-Caetano I, Marques PI, Carvalho F, Barros A, Gromoll J, Bassas L, Seixas S, Gonçalves J, Larriba S, Kliesch S, Palomino-Morales RJ, Carmona FD. Cerván-Martín M, et al. Commun Biol. 2022 Nov 10;5(1):1220. doi: 10.1038/s42003-022-04192-0. Commun Biol. 2022. PMID: 36357561 Free PMC article.
Two genomic regions were associated with the most severe histological pattern of SPGF, defined by Sertoli cell-only (SCO) phenotype, namely the MHC class II gene HLA-DRB1 (rs1136759, P = 1.32E-08, OR = 1.80) and an upstream locus of VRK1 (rs115054029, P = 4.24E-08, …
Two genomic regions were associated with the most severe histological pattern of SPGF, defined by Sertoli cell-only (SCO) phenotype, namely …
Undertreatment of people with major depressive disorder in 21 countries.
Thornicroft G, Chatterji S, Evans-Lacko S, Gruber M, Sampson N, Aguilar-Gaxiola S, Al-Hamzawi A, Alonso J, Andrade L, Borges G, Bruffaerts R, Bunting B, de Almeida JM, Florescu S, de Girolamo G, Gureje O, Haro JM, He Y, Hinkov H, Karam E, Kawakami N, Lee S, Navarro-Mateu F, Piazza M, Posada-Villa J, de Galvis YT, Kessler RC. Thornicroft G, et al. Br J Psychiatry. 2017 Feb;210(2):119-124. doi: 10.1192/bjp.bp.116.188078. Epub 2016 Dec 1. Br J Psychiatry. 2017. PMID: 27908899 Free PMC article.
The endangered California Condor (Gymnogyps californianus) population is exposed to local haemosporidian parasites.
Pacheco MA, Parish CN, Hauck TJ, Aguilar RF, Escalante AA. Pacheco MA, et al. Sci Rep. 2020 Oct 21;10(1):17947. doi: 10.1038/s41598-020-74894-0. Sci Rep. 2020. PMID: 33087805 Free PMC article.
This is the first report of a haemosporidian species infecting California Condors, and the first evidence of P. homopolare circulating in the Condor population from Arizona. Although no evidence of pathogenicity of P. homopolare in Condors was found, this study show …
This is the first report of a haemosporidian species infecting California Condors, and the first evidence of P. homopolare circulatin …
The ovaries of ivermectin-resistant Rhipicephalus microplus strains display proteomic adaptations involving the induction of xenobiotic detoxification and structural remodeling mechanisms.
Álvarez-Sánchez ME, Ruiz-May E, Aguilar-Tipacamú G, Elizalde-Contreras JM, Bojórquez-Velázquez E, Zamora-Briseño JA, Vidal Limón AM, Vázquez-Carrillo LI. Álvarez-Sánchez ME, et al. J Proteomics. 2023 May 30;280:104892. doi: 10.1016/j.jprot.2023.104892. Epub 2023 Mar 29. J Proteomics. 2023. PMID: 36997062
Impact of time to intubation on mortality and pulmonary sequelae in critically ill patients with COVID-19: a prospective cohort study.
González J, Benítez ID, de Gonzalo-Calvo D, Torres G, de Batlle J, Gómez S, Moncusí-Moix A, Carmona P, Santisteve S, Monge A, Gort-Paniello C, Zuil M, Cabo-Gambín R, Manzano Senra C, Vengoechea Aragoncillo JJ, Vaca R, Minguez O, Aguilar M, Ferrer R, Ceccato A, Fernández L, Motos A, Riera J, Menéndez R, Garcia-Gasulla D, Peñuelas O, Labarca G, Caballero J, Barberà C, Torres A, Barbé F; CIBERESUCICOVID Project (COV20/00110, ISCIII). González J, et al. Crit Care. 2022 Jan 10;26(1):18. doi: 10.1186/s13054-021-03882-1. Crit Care. 2022. PMID: 35012662 Free PMC article.
RESULTS: We included 205 patients (140 with early IMV and 65 with delayed IMV). The median [p(25);p(75)] age was 63 [56.0; 70.0] years, and 74.1% were male. ...
RESULTS: We included 205 patients (140 with early IMV and 65 with delayed IMV). The median [p(25);p(75)] age was 63 [56.0; 70. …
29 results