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Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of Rho GTPases in cleft/lip palate development.
Ghassibe-Sabbagh M, El Hajj J, Al Saneh M, El Baba N, Abou Issa J, Al Haddad M, El Atat O, Sabbagh J, Abou Chebel N, El-Sibai M. Ghassibe-Sabbagh M, et al. Among authors: al haddad m. Cells Dev. 2021 Jun;166:203674. doi: 10.1016/j.cdev.2021.203674. Epub 2021 Mar 17. Cells Dev. 2021. PMID: 33994351 Free article.
Dysregulation of Rho GTPases in orofacial cleft patients-derived primary cells leads to impaired cell migration, a potential cause of cleft/lip palate development.
El-Sibai M, El Hajj J, Al Haddad M, El Baba N, Al Saneh M, Daoud Khatoun W, Helaers R, Vikkula M, El Atat O, Sabbagh J, Abou Chebel N, Ghassibe-Sabbagh M. El-Sibai M, et al. Among authors: al haddad m. Cells Dev. 2021 Mar;165:203656. doi: 10.1016/j.cdev.2021.203656. Epub 2021 Jan 16. Cells Dev. 2021. PMID: 34024335 Free article.