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Tissue-resident glial cells associate with tumoral vasculature and promote cancer progression.
Rocha BGS, Picoli CC, Gonçalves BOP, Silva WN, Costa AC, Moraes MM, Costa PAC, Santos GSP, Almeida MR, Silva LM, Singh Y, Falchetti M, Guardia GDA, Guimarães PPG, Russo RC, Resende RR, Pinto MCX, Amorim JH, Azevedo VAC, Kanashiro A, Nakaya HI, Rocha EL, Galante PAF, Mintz A, Frenette PS, Birbrair A. Rocha BGS, et al. Among authors: falchetti m. Angiogenesis. 2023 Feb;26(1):129-166. doi: 10.1007/s10456-022-09858-1. Epub 2022 Oct 1. Angiogenesis. 2023. PMID: 36183032
Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells.
Morris V, Wang D, Li Z, Marion W, Hughes T, Sousa P, Harada T, Sui SH, Naumenko S, Kalfon J, Sensharma P, Falchetti M, Vinicius da Silva R, Candelli T, Schneider P, Margaritis T, Holstege FCP, Pikman Y, Harris M, Stam RW, Orkin SH, Koehler AN, Shalek AK, North TE, Pimkin M, Daley GQ, Lummertz da Rocha E, Rowe RG. Morris V, et al. Among authors: falchetti m. Cell Rep. 2022 Apr 26;39(4):110752. doi: 10.1016/j.celrep.2022.110752. Cell Rep. 2022. PMID: 35476984 Free PMC article.
Subcellular localization of PD-L1 and cell-cycle-dependent expression of nuclear PD-L1 variants: implications for head and neck cancer cell functions and therapeutic efficacy.
Schulz D, Feulner L, Santos Rubenich D, Heimer S, Rohrmüller S, Reinders Y, Falchetti M, Wetzel M, Braganhol E, Lummertz da Rocha E, Schäfer N, Stöckl S, Brockhoff G, Wege AK, Fritsch J, Pohl F, Reichert TE, Ettl T, Bauer RJ. Schulz D, et al. Among authors: falchetti m. Mol Oncol. 2024 Feb;18(2):431-452. doi: 10.1002/1878-0261.13567. Epub 2023 Dec 26. Mol Oncol. 2024. PMID: 38103190 Free PMC article.
COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice.
Gonçalves RM, Delgobo M, Agnes JP, das Neves RN, Falchetti M, Casagrande T, Garcia APV, Vieira TC, Somensi N, Bruxel MA, Mendes DAGB, Rafacho A, Báfica A, Gelain DP, Moreira JCF, Cassali GD, Bishop AJR, Zanotto-Filho A. Gonçalves RM, et al. Among authors: falchetti m. Cancer Lett. 2021 Apr 1;502:44-57. doi: 10.1016/j.canlet.2021.01.003. Epub 2021 Jan 9. Cancer Lett. 2021. PMID: 33429006 Free article.
Thioredoxin reductase-1 levels are associated with NRF2 pathway activation and tumor recurrence in non-small cell lung cancer.
Delgobo M, Gonçalves RM, Delazeri MA, Falchetti M, Zandoná A, Nascimento das Neves R, Almeida K, Fagundes AC, Gelain DP, Fracasso JI, Macêdo GB, Priori L, Bassani N, Bishop AJR, Forcelini CM, Moreira JCF, Zanotto-Filho A. Delgobo M, et al. Among authors: falchetti m. Free Radic Biol Med. 2021 Dec;177:58-71. doi: 10.1016/j.freeradbiomed.2021.10.020. Epub 2021 Oct 19. Free Radic Biol Med. 2021. PMID: 34673143
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