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Repurposing the estrogen receptor modulator raloxifene to treat SARS-CoV-2 infection.
Allegretti M, Cesta MC, Zippoli M, Beccari A, Talarico C, Mantelli F, Bucci EM, Scorzolini L, Nicastri E. Allegretti M, et al. Among authors: zippoli m. Cell Death Differ. 2022 Jan;29(1):156-166. doi: 10.1038/s41418-021-00844-6. Epub 2021 Aug 17. Cell Death Differ. 2022. PMID: 34404919 Free PMC article. Review.
Characterization of raloxifene as a potential pharmacological agent against SARS-CoV-2 and its variants.
Iaconis D, Bordi L, Matusali G, Talarico C, Manelfi C, Cesta MC, Zippoli M, Caccuri F, Bugatti A, Zani A, Filippini F, Scorzolini L, Gobbi M, Beeg M, Piotti A, Montopoli M, Cocetta V, Bressan S, Bucci EM, Caruso A, Nicastri E, Allegretti M, Beccari AR. Iaconis D, et al. Among authors: zippoli m. Cell Death Dis. 2022 May 25;13(5):498. doi: 10.1038/s41419-022-04961-z. Cell Death Dis. 2022. PMID: 35614039 Free PMC article.
In vivo activity of an azole series of CCR2 antagonists.
Smethurst CA, Bevan N, Brooks C, Emmons A, Gough PJ, Mookherjee C, Moores K, Peace S, Philp J, Piercy V, Watson SP, Zippoli M. Smethurst CA, et al. Among authors: zippoli m. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7252-5. doi: 10.1016/j.bmcl.2012.09.020. Epub 2012 Sep 23. Bioorg Med Chem Lett. 2012. PMID: 23079519
Identification of a sulfonamide series of CCR2 antagonists.
Peace S, Philp J, Brooks C, Piercy V, Moores K, Smethurst C, Watson S, Gaines S, Zippoli M, Mookherjee C, Ife R. Peace S, et al. Among authors: zippoli m. Bioorg Med Chem Lett. 2010 Jul 1;20(13):3961-4. doi: 10.1016/j.bmcl.2010.04.142. Epub 2010 May 7. Bioorg Med Chem Lett. 2010. PMID: 20627722