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2-Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-β-Lactamase Classes by Maintaining a Conserved Binding Mode.
Hinchliffe P, Moreno DM, Rossi MA, Mojica MF, Martinez V, Villamil V, Spellberg B, Drusano GL, Banchio C, Mahler G, Bonomo RA, Vila AJ, Spencer J. Hinchliffe P, et al. Among authors: rossi ma. ACS Infect Dis. 2021 Sep 10;7(9):2697-2706. doi: 10.1021/acsinfecdis.1c00194. Epub 2021 Aug 6. ACS Infect Dis. 2021. PMID: 34355567 Free PMC article.
Rational Design of Benzobisheterocycle Metallo-β-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes.
Villamil V, Rossi MA, Mojica MF, Hinchliffe P, Martínez V, Castillo V, Saiz C, Banchio C, Macías MA, Spencer J, Bonomo RA, Vila A, Moreno DM, Mahler G. Villamil V, et al. Among authors: rossi ma. J Med Chem. 2024 Mar 14;67(5):3795-3812. doi: 10.1021/acs.jmedchem.3c02209. Epub 2024 Feb 19. J Med Chem. 2024. PMID: 38373290