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Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b.
Lenza MP, Egia-Mendikute L, Antoñana-Vildosola A, Soares CO, Coelho H, Corzana F, Bosch A, Manisha P, Quintana JI, Oyenarte I, Unione L, Moure MJ, Azkargorta M, Atxabal U, Sobczak K, Elortza F, Sutherland JD, Barrio R, Marcelo F, Jiménez-Barbero J, Palazon A, Ereño-Orbea J. Lenza MP, et al. Nat Commun. 2023 Jun 13;14(1):3496. doi: 10.1038/s41467-023-39119-8. Nat Commun. 2023. PMID: 37311743 Free PMC article.
Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody.
Lenza MP, Atxabal U, Nycholat C, Oyenarte I, Franconetti A, Quintana JI, Delgado S, Núñez-Franco R, Garnica Marroquín CT, Coelho H, Unione L, Jiménez-Oses G, Marcelo F, Schubert M, Paulson JC, Jiménez-Barbero J, Ereño-Orbea J. Lenza MP, et al. JACS Au. 2022 Dec 23;3(1):204-215. doi: 10.1021/jacsau.2c00592. eCollection 2023 Jan 23. JACS Au. 2022. PMID: 36711084 Free PMC article.
Glycoprofile Analysis of an Intact Glycoprotein As Inferred by NMR Spectroscopy.
Unione L, Lenza MP, Ardá A, Urquiza P, Laín A, Falcón-Pérez JM, Jiménez-Barbero J, Millet O. Unione L, et al. Among authors: lenza mp. ACS Cent Sci. 2019 Sep 25;5(9):1554-1561. doi: 10.1021/acscentsci.9b00540. Epub 2019 Jul 24. ACS Cent Sci. 2019. PMID: 31572782 Free PMC article.
Structural Characterization of N-Linked Glycans in the Receptor Binding Domain of the SARS-CoV-2 Spike Protein and their Interactions with Human Lectins.
Lenza MP, Oyenarte I, Diercks T, Quintana JI, Gimeno A, Coelho H, Diniz A, Peccati F, Delgado S, Bosch A, Valle M, Millet O, Abrescia NGA, Palazón A, Marcelo F, Jiménez-Osés G, Jiménez-Barbero J, Ardá A, Ereño-Orbea J. Lenza MP, et al. Angew Chem Int Ed Engl. 2020 Dec 21;59(52):23763-23771. doi: 10.1002/anie.202011015. Epub 2020 Oct 22. Angew Chem Int Ed Engl. 2020. PMID: 32915505 Free PMC article.
Unraveling Molecular Recognition of Glycan Ligands by Siglec-9 via NMR Spectroscopy and Molecular Dynamics Modeling.
Atxabal U, Nycholat C, Pröpster JM, Fernández A, Oyenarte I, Lenza MP, Franconetti A, Soares CO, Coelho H, Marcelo F, Schubert M, Paulson JC, Jiménez-Barbero J, Ereño-Orbea J. Atxabal U, et al. Among authors: lenza mp. ACS Chem Biol. 2024 Feb 16;19(2):483-496. doi: 10.1021/acschembio.3c00664. Epub 2024 Feb 7. ACS Chem Biol. 2024. PMID: 38321945 Free PMC article.