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Whole-genome CRISPR screening identifies N-glycosylation as a genetic and therapeutic vulnerability in CALR-mutant MPNs.
Jutzi JS, Marneth AE, Ciboddo M, Guerra-Moreno A, Jiménez-Santos MJ, Kosmidou A, Dressman JW, Liang H, Hamel R, Lozano P, Rumi E, Doench JG, Gotlib J, Krishnan A, Elf S, Al-Shahrour F, Mullally A. Jutzi JS, et al. Among authors: jimenez santos mj. Blood. 2022 Sep 15;140(11):1291-1304. doi: 10.1182/blood.2022015629. Blood. 2022. PMID: 35763665 Free PMC article.
CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response.
Jutzi JS, Marneth AE, Jiménez-Santos MJ, Hem J, Guerra-Moreno A, Rolles B, Bhatt S, Myers SA, Carr SA, Hong Y, Pozdnyakova O, van Galen P, Al-Shahrour F, Nam AS, Mullally A. Jutzi JS, et al. Among authors: jimenez santos mj. Leukemia. 2023 Feb;37(2):359-369. doi: 10.1038/s41375-022-01781-0. Epub 2022 Dec 6. Leukemia. 2023. PMID: 36473980
Bioinformatics roadmap for therapy selection in cancer genomics.
Jiménez-Santos MJ, García-Martín S, Fustero-Torre C, Di Domenico T, Gómez-López G, Al-Shahrour F. Jiménez-Santos MJ, et al. Mol Oncol. 2022 Nov;16(21):3881-3908. doi: 10.1002/1878-0261.13286. Epub 2022 Aug 20. Mol Oncol. 2022. PMID: 35811332 Free PMC article. Review.
bollito: a flexible pipeline for comprehensive single-cell RNA-seq analyses.
García-Jimeno L, Fustero-Torre C, Jiménez-Santos MJ, Gómez-López G, Di Domenico T, Al-Shahrour F. García-Jimeno L, et al. Among authors: jimenez santos mj. Bioinformatics. 2022 Jan 27;38(4):1155-1156. doi: 10.1093/bioinformatics/btab758. Bioinformatics. 2022. PMID: 34788788
PanDrugs2: prioritizing cancer therapies using integrated individual multi-omics data.
Jiménez-Santos MJ, Nogueira-Rodríguez A, Piñeiro-Yáñez E, López-Fernández H, García-Martín S, Gómez-Plana P, Reboiro-Jato M, Gómez-López G, Glez-Peña D, Al-Shahrour F. Jiménez-Santos MJ, et al. Nucleic Acids Res. 2023 Jul 5;51(W1):W411-W418. doi: 10.1093/nar/gkad412. Nucleic Acids Res. 2023. PMID: 37207338 Free PMC article.
Beyondcell: targeting cancer therapeutic heterogeneity in single-cell RNA-seq data.
Fustero-Torre C, Jiménez-Santos MJ, García-Martín S, Carretero-Puche C, García-Jimeno L, Ivanchuk V, Di Domenico T, Gómez-López G, Al-Shahrour F. Fustero-Torre C, et al. Among authors: jimenez santos mj. Genome Med. 2021 Dec 16;13(1):187. doi: 10.1186/s13073-021-01001-x. Genome Med. 2021. PMID: 34911571 Free PMC article.