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Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses.
Silva-Pilipich N, Blanco E, Lozano T, Martisova E, Igea A, Herrador-Cañete G, Ballesteros-Briones MC, Gorraiz M, Sarrión P, González-Sapienza G, Lasarte JJ, Vanrell L, Smerdou C. Silva-Pilipich N, et al. Among authors: ballesteros briones mc. Cancer Lett. 2023 May 1;561:216139. doi: 10.1016/j.canlet.2023.216139. Epub 2023 Mar 29. Cancer Lett. 2023. PMID: 37001752 Free article.
A new generation of vaccines based on alphavirus self-amplifying RNA.
Ballesteros-Briones MC, Silva-Pilipich N, Herrador-Cañete G, Vanrell L, Smerdou C. Ballesteros-Briones MC, et al. Curr Opin Virol. 2020 Oct;44:145-153. doi: 10.1016/j.coviro.2020.08.003. Epub 2020 Sep 6. Curr Opin Virol. 2020. PMID: 32898764 Free PMC article. Review.
Optimization of a GDNF production method based on Semliki Forest virus vector.
Torres-Ortega PV, Smerdou C, Ansorena E, Ballesteros-Briones MC, Martisova E, Garbayo E, Blanco-Prieto MJ. Torres-Ortega PV, et al. Among authors: ballesteros briones mc. Eur J Pharm Sci. 2021 Apr 1;159:105726. doi: 10.1016/j.ejps.2021.105726. Epub 2021 Jan 19. Eur J Pharm Sci. 2021. PMID: 33482318 Free article.
Capsid-deficient alphaviruses generate propagative infectious microvesicles at the plasma membrane.
Ruiz-Guillen M, Gabev E, Quetglas JI, Casales E, Ballesteros-Briones MC, Poutou J, Aranda A, Martisova E, Bezunartea J, Ondiviela M, Prieto J, Hernandez-Alcoceba R, Abrescia NG, Smerdou C. Ruiz-Guillen M, et al. Among authors: ballesteros briones mc. Cell Mol Life Sci. 2016 Oct;73(20):3897-916. doi: 10.1007/s00018-016-2230-1. Epub 2016 Apr 27. Cell Mol Life Sci. 2016. PMID: 27117550 Free PMC article.
Idiotype vaccines produced with a non-cytopathic alphavirus self-amplifying RNA vector induce antitumor responses in a murine model of B-cell lymphoma.
Casales E, Martisova E, Villanueva H, de Cerio ALD, Inoges S, Silva-Pilipich N, Ballesteros-Briones MC, Aranda A, Bezunartea J, Bendandi M, Pastor F, Smerdou C. Casales E, et al. Among authors: ballesteros briones mc. Sci Rep. 2021 Nov 2;11(1):21427. doi: 10.1038/s41598-021-00787-5. Sci Rep. 2021. PMID: 34728659 Free PMC article.
Short-Term Local Expression of a PD-L1 Blocking Antibody from a Self-Replicating RNA Vector Induces Potent Antitumor Responses.
Ballesteros-Briones MC, Martisova E, Casales E, Silva-Pilipich N, Buñuales M, Galindo J, Mancheño U, Gorraiz M, Lasarte JJ, Kochan G, Escors D, Sanchez-Paulete AR, Melero I, Prieto J, Hernandez-Alcoceba R, Hervas-Stubbs S, Smerdou C. Ballesteros-Briones MC, et al. Mol Ther. 2019 Nov 6;27(11):1892-1905. doi: 10.1016/j.ymthe.2019.09.016. Epub 2019 Sep 16. Mol Ther. 2019. PMID: 31563534 Free PMC article.
Intratumoral Immunotherapy with XCL1 and sFlt3L Encoded in Recombinant Semliki Forest Virus-Derived Vectors Fosters Dendritic Cell-Mediated T-cell Cross-Priming.
Sánchez-Paulete AR, Teijeira Á, Quetglas JI, Rodríguez-Ruiz ME, Sánchez-Arráez Á, Labiano S, Etxeberria I, Azpilikueta A, Bolaños E, Ballesteros-Briones MC, Casares N, Quezada SA, Berraondo P, Sancho D, Smerdou C, Melero I. Sánchez-Paulete AR, et al. Among authors: ballesteros briones mc. Cancer Res. 2018 Dec 1;78(23):6643-6654. doi: 10.1158/0008-5472.CAN-18-0933. Epub 2018 Oct 8. Cancer Res. 2018. PMID: 30297531
Adenovirus-Mediated Inducible Expression of a PD-L1 Blocking Antibody in Combination with Macrophage Depletion Improves Survival in a Mouse Model of Peritoneal Carcinomatosis.
Buñuales M, Ballesteros-Briones MC, Gonzalez-Aparicio M, Hervas-Stubbs S, Martisova E, Mancheño U, Ricobaraza A, Lumbreras S, Smerdou C, Hernandez-Alcoceba R. Buñuales M, et al. Among authors: ballesteros briones mc. Int J Mol Sci. 2021 Apr 17;22(8):4176. doi: 10.3390/ijms22084176. Int J Mol Sci. 2021. PMID: 33920699 Free PMC article.