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Page 1
Inhibition of α-Synuclein Aggregation and Mature Fibril Disassembling With a Minimalistic Compound, ZPDm.
Peña-Díaz S, Pujols J, Pinheiro F, Santos J, Pallarés I, Navarro S, Conde-Gimenez M, García J, Salvatella X, Dalfó E, Sancho J, Ventura S. Peña-Díaz S, et al. Among authors: conde gimenez m. Front Bioeng Biotechnol. 2020 Oct 16;8:588947. doi: 10.3389/fbioe.2020.588947. eCollection 2020. Front Bioeng Biotechnol. 2020. PMID: 33178678 Free PMC article.
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons.
Pujols J, Peña-Díaz S, Lázaro DF, Peccati F, Pinheiro F, González D, Carija A, Navarro S, Conde-Giménez M, García J, Guardiola S, Giralt E, Salvatella X, Sancho J, Sodupe M, Outeiro TF, Dalfó E, Ventura S. Pujols J, et al. Among authors: conde gimenez m. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10481-10486. doi: 10.1073/pnas.1804198115. Epub 2018 Sep 24. Proc Natl Acad Sci U S A. 2018. PMID: 30249646 Free PMC article.
Selective Targeting of Human and Animal Pathogens of the Helicobacter Genus by Flavodoxin Inhibitors: Efficacy, Synergy, Resistance and Mechanistic Studies.
Salillas S, Galano-Frutos JJ, Mahía A, Maity R, Conde-Giménez M, Anoz-Carbonell E, Berlamont H, Velazquez-Campoy A, Touati E, Mamat U, Schaible UE, Gálvez JA, Díaz-de-Villegas MD, Haesebrouck F, Aínsa JA, Sancho J. Salillas S, et al. Among authors: conde gimenez m. Int J Mol Sci. 2021 Sep 20;22(18):10137. doi: 10.3390/ijms221810137. Int J Mol Sci. 2021. PMID: 34576300 Free PMC article.
A pyrene-inhibitor fluorescent probe with large Stokes shift for the staining of Aβ1-42, α-synuclein, and amylin amyloid fibrils as well as amyloid-containing Staphylococcus aureus biofilms.
Mahía A, Conde-Giménez M, Salillas S, Pallarés I, Galano-Frutos JJ, Lasa Í, Ventura S, Díaz-de-Villegas MD, Gálvez JA, Sancho J. Mahía A, et al. Among authors: conde gimenez m. Anal Bioanal Chem. 2019 Jan;411(1):251-265. doi: 10.1007/s00216-018-1433-8. Epub 2018 Nov 9. Anal Bioanal Chem. 2019. PMID: 30411148