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Page 1
Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis.
Voskens C, Stoica D, Rosenberg M, Vitali F, Zundler S, Ganslmayer M, Knott H, Wiesinger M, Wunder J, Kummer M, Siegmund B, Schnoy E, Rath T, Hartmann A, Hackstein H, Schuler-Thurner B, Berking C, Schuler G, Atreya R, Neurath MF. Voskens C, et al. Among authors: wiesinger m. Gut. 2023 Jan;72(1):49-53. doi: 10.1136/gutjnl-2022-327075. Epub 2022 Apr 15. Gut. 2023. PMID: 35428657 Free PMC article. Clinical Trial.
Increased Motility and Suppression of Ex Vivo-Expanded Regulatory T Cells Designed for Adoptive Transfer Therapy in Ulcerative Colitis.
Müller TM, Liu LJ, Czerwinski T, Wiesinger M, Dedden M, Paap EM, Ullrich KA, Atreya I, Siegmund B, Atreya R, Fabry B, Berking C, Neurath MF, Zundler S, Voskens CJ. Müller TM, et al. Among authors: wiesinger m. Cell Mol Gastroenterol Hepatol. 2023;16(1):183-187.e2. doi: 10.1016/j.jcmgh.2023.04.002. Epub 2023 Apr 20. Cell Mol Gastroenterol Hepatol. 2023. PMID: 37085136 Free PMC article. No abstract available.
Safety and tolerability of a single infusion of autologous ex vivo expanded regulatory T cells in adults with ulcerative colitis (ER-TREG 01): protocol of a phase 1, open-label, fast-track dose-escalation clinical trial.
Voskens CJ, Stoica D, Roessner S, Vitali F, Zundler S, Rosenberg M, Wiesinger M, Wunder J, Siegmund B, Schuler-Thurner B, Schuler G, Berking C, Atreya R, Neurath MF. Voskens CJ, et al. Among authors: wiesinger m. BMJ Open. 2021 Dec 8;11(12):e049208. doi: 10.1136/bmjopen-2021-049208. BMJ Open. 2021. PMID: 34880013 Free PMC article.
Automated Good Manufacturing Practice-compliant generation of human monocyte-derived dendritic cells from a complete apheresis product using a hollow-fiber bioreactor system overcomes a major hurdle in the manufacture of dendritic cells for cancer vaccines.
Uslu U, Erdmann M, Wiesinger M, Schuler G, Schuler-Thurner B. Uslu U, et al. Among authors: wiesinger m. Cytotherapy. 2019 Nov;21(11):1166-1178. doi: 10.1016/j.jcyt.2019.09.001. Epub 2019 Oct 23. Cytotherapy. 2019. PMID: 31668486
Denileukin diftitox (ONTAK) induces a tolerogenic phenotype in dendritic cells and stimulates survival of resting Treg.
Baur AS, Lutz MB, Schierer S, Beltrame L, Theiner G, Zinser E, Ostalecki C, Heidkamp G, Haendle I, Erdmann M, Wiesinger M, Leisgang W, Gross S, Pommer AJ, Kämpgen E, Dudziak D, Steinkasserer A, Cavalieri D, Schuler-Thurner B, Schuler G. Baur AS, et al. Among authors: wiesinger m. Blood. 2013 Sep 26;122(13):2185-94. doi: 10.1182/blood-2012-09-456988. Epub 2013 Aug 19. Blood. 2013. PMID: 23958949 Free article. Clinical Trial.
Good Manufacturing Practice-Compliant Production and Lot-Release of Ex Vivo Expanded Regulatory T Cells As Basis for Treatment of Patients with Autoimmune and Inflammatory Disorders.
Wiesinger M, Stoica D, Roessner S, Lorenz C, Fischer A, Atreya R, Neufert CF, Atreya I, Scheffold A, Schuler-Thurner B, Neurath MF, Schuler G, Voskens CJ. Wiesinger M, et al. Front Immunol. 2017 Oct 26;8:1371. doi: 10.3389/fimmu.2017.01371. eCollection 2017. Front Immunol. 2017. PMID: 29123521 Free PMC article.