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A chemoproteoinformatics approach demonstrates that aspirin increases sensitivity to MEK inhibition by directly binding to RPS5.
Watanabe M, Boku S, Kobayashi K, Kurumida Y, Sukeno M, Masuda M, Mizushima K, Kato C, Iizumi Y, Hirota K, Naito Y, Mutoh M, Kameda T, Sakai T. Watanabe M, et al. Among authors: sukeno m. PNAS Nexus. 2022 May 16;1(2):pgac059. doi: 10.1093/pnasnexus/pgac059. eCollection 2022 May. PNAS Nexus. 2022. PMID: 36713317 Free PMC article.
Mevalonate pathway blockage enhances the efficacy of mTOR inhibitors with the activation of retinoblastoma protein in renal cell carcinoma.
Hagiwara N, Watanabe M, Iizuka-Ohashi M, Yokota I, Toriyama S, Sukeno M, Tomosugi M, Sowa Y, Hongo F, Mikami K, Soh J, Fujito A, Miyashita H, Morioka Y, Miki T, Ukimura O, Sakai T. Hagiwara N, et al. Among authors: sukeno m. Cancer Lett. 2018 Sep 1;431:182-189. doi: 10.1016/j.canlet.2018.05.025. Epub 2018 May 17. Cancer Lett. 2018. PMID: 29778569
14 results