Makoto Hirasawa - Search Results

Year	Number of Results
2005	1
2013	2
2014	1
2015	1
2017	2
2018	2
2019	1
2020	3
2022	4
2023	1
2024	0

1

Potent and Selective PTDSS1 Inhibitors Induce Collateral Lethality in Cancers with PTDSS2 Deletion.

Yoshihama Y, Namiki H, Kato T, Shimazaki N, Takaishi S, Kadoshima-Yamaoka K, Yukinaga H, Maeda N, Shibutani T, Fujimoto K, Hirasawa M, Goto H, Wada N, Tsutsumi S, Hirota Y, Ishikawa T, Yamamoto S. Yoshihama Y, et al. Among authors: hirasawa m. Cancer Res. 2022 Nov 2;82(21):4031-4043. doi: 10.1158/0008-5472.CAN-22-1006. Cancer Res. 2022. PMID: 36054550

2

Revisiting Cerebrospinal Fluid Flow Direction and Rate in Physiologically Based Pharmacokinetic Model.

Hirasawa M, de Lange ECM. Hirasawa M, et al. Pharmaceutics. 2022 Aug 24;14(9):1764. doi: 10.3390/pharmaceutics14091764. Pharmaceutics. 2022. PMID: 36145511 Free PMC article.

3

RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer.

Yenerall P, Das AK, Wang S, Kollipara RK, Li LS, Villalobos P, Flaming J, Lin YF, Huffman K, Timmons BC, Gilbreath C, Sonavane R, Kinch LN, Rodriguez-Canales J, Moran C, Behrens C, Hirasawa M, Takata T, Murakami R, Iwanaga K, Chen BPC, Grishin NV, Raj GV, Wistuba II, Minna JD, Kittler R. Yenerall P, et al. Among authors: hirasawa m. Cell Chem Biol. 2020 Jan 16;27(1):105-121.e14. doi: 10.1016/j.chembiol.2019.12.005. Epub 2019 Dec 26. Cell Chem Biol. 2020. PMID: 31883965 Free PMC article.

4

The Extension of the LeiCNS-PK3.0 Model in Combination with the "Handshake" Approach to Understand Brain Tumor Pathophysiology.

Hirasawa M, Saleh MAA, de Lange ECM. Hirasawa M, et al. Pharm Res. 2022 Jul;39(7):1343-1361. doi: 10.1007/s11095-021-03154-1. Epub 2022 Mar 7. Pharm Res. 2022. PMID: 35258766 Free PMC article.

5

The PBPK LeiCNS-PK3.0 framework predicts Nirmatrelvir (but not Remdesivir or Molnupiravir) to achieve effective concentrations against SARS-CoV-2 in human brain cells.

Saleh MAA, Hirasawa M, Sun M, Gülave B, Elassaiss-Schaap J, de Lange ECM. Saleh MAA, et al. Among authors: hirasawa m. Eur J Pharm Sci. 2023 Feb 1;181:106345. doi: 10.1016/j.ejps.2022.106345. Epub 2022 Nov 30. Eur J Pharm Sci. 2023. PMID: 36462547 Free PMC article.

6

Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity.

Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, Inoue M, Olson SH, Prusiner SB, Conrad J, Paras NA. Grandjean JM, et al. Among authors: hirasawa m. ACS Med Chem Lett. 2020 Jan 30;11(2):127-132. doi: 10.1021/acsmedchemlett.9b00480. eCollection 2020 Feb 13. ACS Med Chem Lett. 2020. PMID: 32071678 Free PMC article.

7

Detection of Abacavir-Induced Structural Alterations in Human Leukocyte Antigen-B*57 : 01 Using Phage Display.

Shirayanagi T, Aoki S, Fujimori S, Watanabe K, Aida T, Hirasawa M, Kumagai K, Hoshino T, Ito K. Shirayanagi T, et al. Among authors: hirasawa m. Biol Pharm Bull. 2020;43(6):1007-1015. doi: 10.1248/bpb.b20-00102. Biol Pharm Bull. 2020. PMID: 32475910 Free article.

8

Interaction of Nevirapine with the Peptide Binding Groove of HLA-DRB1*01:01 and Its Effect on the Conformation of HLA-Peptide Complex.

Hirasawa M, Hagihara K, Abe K, Ando O, Hirayama N. Hirasawa M, et al. Int J Mol Sci. 2018 Jun 4;19(6):1660. doi: 10.3390/ijms19061660. Int J Mol Sci. 2018. PMID: 29867033 Free PMC article.

9

In Silico and In Vitro Analysis of Interaction between Ximelagatran and Human Leukocyte Antigen (HLA)-DRB1*07:01.

Hirasawa M, Hagihara K, Abe K, Ando O, Hirayama N. Hirasawa M, et al. Int J Mol Sci. 2017 Mar 24;18(4):694. doi: 10.3390/ijms18040694. Int J Mol Sci. 2017. PMID: 28338626 Free PMC article.

10

Simultaneous determination of the size and concentration of fine bubbles in water by laser-light scattering.

Takahashi K, Ohuchi S, Saito K, Hirasawa M, Sakurai H. Takahashi K, et al. Among authors: hirasawa m. Appl Opt. 2018 Jan 10;57(2):225-229. doi: 10.1364/AO.57.000225. Appl Opt. 2018. PMID: 29328168

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