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KCl-induced repetitive cortical spreading depression inhibiting trigeminal neuronal firing is mediated by 5-HT1B/1D and opioid receptors.
Supronsinchai W, Hoffmann J, Akerman S, Goadsby PJ. Supronsinchai W, et al. Cephalalgia. 2022 Nov;42(13):1339-1348. doi: 10.1177/03331024221112998. Epub 2022 Jul 13. Cephalalgia. 2022. PMID: 35833238 Free PMC article.
This response was reversed by the selective 5-HT(1B/1D) receptor antagonist, GR127935 (3 mg/kg; n = 6, iv), and a non-selective opioid receptor antagonist, naloxone (1.5 mg/kg; n = 6, iv), five minutes after injection. To determine the role of the nucleus raphe magnus in t …
This response was reversed by the selective 5-HT(1B/1D) receptor antagonist, GR127935 (3 mg/kg; n = 6, iv), and a non-selective opioid recep …
Patterns of fos expression in the rostral medulla and caudal pons evoked by noxious craniovascular stimulation and periaqueductal gray stimulation in the cat.
Knight YE, Classey JD, Lasalandra MP, Akerman S, Kowacs F, Hoskin KL, Goadsby PJ. Knight YE, et al. Brain Res. 2005 May 31;1045(1-2):1-11. doi: 10.1016/j.brainres.2005.01.091. Brain Res. 2005. PMID: 15910757
The structures examined for fos were the trigeminal nucleus, infratrigeminal nucleus, reticular nuclei, nucleus raphe magnus, pontine blink premotor area, and superior salivatory nucleus. ...After PAG with SSS stimulation, on the side ipsilateral to the site of PAG stimula …
The structures examined for fos were the trigeminal nucleus, infratrigeminal nucleus, reticular nuclei, nucleus raphe magnus, pontine …