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Discovery of a series of ester-substituted NLRP3 inflammasome inhibitors.
Bioorg Med Chem Lett. 2020 Dec 1;30(23):127560. doi: 10.1016/j.bmcl.2020.127560. Epub 2020 Sep 18.
Bioorg Med Chem Lett. 2020.
PMID: 32956781
Novel (S)-1,3,4,12a-tetrahydropyrazino[2,1-c][1,4]benzodiazepine-6,12(2H,11H)-dione derivatives: Selective inhibition of MV-4-11 biphenotypic B myelomonocytic leukemia cells' growth is accompanied by reactive oxygen species overproduction and apoptosis.
Mieczkowski A, Psurski M, Bagiński M, Bieszczad B, Mroczkowska M, Wilczek M, Czajkowska J, Trzybiński D, Woźniak K, Wietrzyk J.
Mieczkowski A, et al. Among authors: mroczkowska m.
Bioorg Med Chem Lett. 2018 Feb 15;28(4):618-625. doi: 10.1016/j.bmcl.2018.01.034. Epub 2018 Jan 31.
Bioorg Med Chem Lett. 2018.
PMID: 29395971
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