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Resolution of liver fibrosis requires myeloid cell-driven sinusoidal angiogenesis.
Kantari-Mimoun C, Castells M, Klose R, Meinecke AK, Lemberger UJ, Rautou PE, Pinot-Roussel H, Badoual C, Schrödter K, Österreicher CH, Fandrey J, Stockmann C. Kantari-Mimoun C, et al. Among authors: castells m. Hepatology. 2015 Jun;61(6):2042-55. doi: 10.1002/hep.27635. Epub 2015 Mar 10. Hepatology. 2015. PMID: 25475053
Loss of HIF-1α in natural killer cells inhibits tumour growth by stimulating non-productive angiogenesis.
Krzywinska E, Kantari-Mimoun C, Kerdiles Y, Sobecki M, Isagawa T, Gotthardt D, Castells M, Haubold J, Millien C, Viel T, Tavitian B, Takeda N, Fandrey J, Vivier E, Sexl V, Stockmann C. Krzywinska E, et al. Among authors: castells m. Nat Commun. 2017 Nov 17;8(1):1597. doi: 10.1038/s41467-017-01599-w. Nat Commun. 2017. PMID: 29150606 Free PMC article.
Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice.
Kantari-Mimoun C, Krzywinska E, Castells M, Milien C, Klose R, Meinecke AK, Lemberger U, Mathivet T, Gojkovic M, Schrödter K, Österreicher C, Fandrey J, Rundqvist H, Stockmann C. Kantari-Mimoun C, et al. Among authors: castells m. Oncotarget. 2017 Feb 28;8(9):15085-15100. doi: 10.18632/oncotarget.14749. Oncotarget. 2017. PMID: 28118605 Free PMC article.