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The 2021 European Alliance of Associations for Rheumatology/American College of Rheumatology points to consider for diagnosis and management of autoinflammatory type I interferonopathies: CANDLE/PRAAS, SAVI and AGS.
Cetin Gedik K, Lamot L, Romano M, Demirkaya E, Piskin D, Torreggiani S, Adang LA, Armangue T, Barchus K, Cordova DR, Crow YJ, Dale RC, Durrant KL, Eleftheriou D, Fazzi EM, Gattorno M, Gavazzi F, Hanson EP, Lee-Kirsch MA, Montealegre Sanchez GA, Neven B, Orcesi S, Ozen S, Poli MC, Schumacher E, Tonduti D, Uss K, Aletaha D, Feldman BM, Vanderver A, Brogan PA, Goldbach-Mansky R. Cetin Gedik K, et al. Ann Rheum Dis. 2022 May;81(5):601-613. doi: 10.1136/annrheumdis-2021-221814. Epub 2022 Jan 27. Ann Rheum Dis. 2022. PMID: 35086813 Free PMC article.
OBJECTIVE: Autoinflammatory type I interferonopathies, chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature/proteasome-associated autoinflammatory syndrome (CANDLE/PRAAS), stimulator of interferon genes (STING)-associated vasculopathy with o …
OBJECTIVE: Autoinflammatory type I interferonopathies, chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature/ …
Turn-of-the-candle effect in bitcoin returns.
Shanaev S, Vasenin M, Stepanov R. Shanaev S, et al. Heliyon. 2023 Mar 2;9(3):e14236. doi: 10.1016/j.heliyon.2023.e14236. eCollection 2023 Mar. Heliyon. 2023. PMID: 36938429 Free PMC article.
The effect is consistent across Bitcoin exchanges, in quantile regression models, and TGARCH-M estimations with heavy tails, and persist in out-of-sample tests. A high-frequency strategy that exploits this "turn-of-the-candle" effect can be net-outperforming with in …
The effect is consistent across Bitcoin exchanges, in quantile regression models, and TGARCH-M estimations with heavy tails, and pers …
Prenatal exposure to particulate matter and placental gene expression.
Enquobahrie DA, MacDonald J, Hussey M, Bammler TK, Loftus CT, Paquette AG, Byington N, Marsit CJ, Szpiro A, Kaufman JD, LeWinn KZ, Bush NR, Tylavsky F, Karr CJ, Sathyanarayana S. Enquobahrie DA, et al. Environ Int. 2022 Jul;165:107310. doi: 10.1016/j.envint.2022.107310. Epub 2022 May 25. Environ Int. 2022. PMID: 35653832 Free PMC article.

False discovery rate (FDR < 0.10) was used to correct for multiple testing. RESULTS: Mean PM(2.5) estimate was 10.5-10.7 mug/m(3) for CANDLE and 6.0-6.3 mug/m(3) for GAPPS participants. In CANDLE, expression of 13 (11 upregulated and 2 downregulated

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False discovery rate (FDR < 0.10) was used to correct for multiple testing. RESULTS: Mean PM(2.5) estimate was 10.5-10.7 mug/m(3)

…
Airway and systemic biomarkers of health effects after short-term exposure to indoor ultrafine particles from cooking and candles - A randomized controlled double-blind crossover study among mild asthmatic subjects.
Laursen KR, Christensen NV, Mulder FA, Schullehner J, Hoffmann HJ, Jensen A, Møller P, Loft S, Olin AC, Rasmussen BB, Rosati B, Strandberg B, Glasius M, Bilde M, Sigsgaard T; Climate Chamber Group. Laursen KR, et al. Part Fibre Toxicol. 2023 Jul 10;20(1):26. doi: 10.1186/s12989-023-00537-7. Part Fibre Toxicol. 2023. PMID: 37430267 Free PMC article. Clinical Trial.
Thirty-six non-smoking asthmatics participated in a randomized controlled double-blind crossover study attending three exposure sessions (mean PM(2.5) g/m(3)(;) polycyclic aromatic hydrocarbons ng/m(3)): (a) air mixed with emissions from cooking (96.1; 1.1), (b) air …
Thirty-six non-smoking asthmatics participated in a randomized controlled double-blind crossover study attending three exposure sessions (me …
[Giant viruses: update, enigmas, controversies and perspectives].
Claverie JM, Abergel C. Claverie JM, et al. Med Sci (Paris). 2016 Dec;32(12):1087-1096. doi: 10.1051/medsci/20163212012. Epub 2017 Jan 3. Med Sci (Paris). 2016. PMID: 28044972 Free article. Review. French.
Unlike microbes known in his time, the first virus (that of tobacco mosaic disease) was discovered by Ivanoski in 1892 because it was not retained by Chamberland's porcelain candles. For more than a century afterward, viruses were equated with this simple property that is …
Unlike microbes known in his time, the first virus (that of tobacco mosaic disease) was discovered by Ivanoski in 1892 because it was not re …
The Chemical History of a Bubble.
Suslick KS, Eddingsaas NC, Flannigan DJ, Hopkins SD, Xu H. Suslick KS, et al. Acc Chem Res. 2018 Sep 18;51(9):2169-2178. doi: 10.1021/acs.accounts.8b00088. Epub 2018 May 17. Acc Chem Res. 2018. PMID: 29771111
Our understanding of the conditions created during cavitation has informed the applications of ultrasound to a wide range of chemical applications, from nanomaterials to synthetically useful organic reactions to biomedical and pharmaceutical uses. Indeed, we echo Michael Faraday' …
Our understanding of the conditions created during cavitation has informed the applications of ultrasound to a wide range of chemical applic …
Genetics of proteasome diseases.
Gomes AV. Gomes AV. Scientifica (Cairo). 2013;2013:637629. doi: 10.1155/2013/637629. Epub 2013 Dec 30. Scientifica (Cairo). 2013. PMID: 24490108 Free PMC article.
It has recently been shown that mutations and polymorphisms in the immunoproteasome catalytic subunit PSMB8 are associated with several inflammatory and autoinflammatory diseases including Nakajo-Nishimura syndrome, CANDLE syndrome, and intestinal M. tuberculosis in …
It has recently been shown that mutations and polymorphisms in the immunoproteasome catalytic subunit PSMB8 are associated with several infl …
Dissolving Candlelit Microneedle for Chronic Inflammatory Skin Diseases.
Ohn J, Jang M, Kang BM, Yang H, Hong JT, Kim KH, Kwon O, Jung H. Ohn J, et al. Adv Sci (Weinh). 2021 May 7;8(14):2004873. doi: 10.1002/advs.202004873. eCollection 2021 Jul. Adv Sci (Weinh). 2021. PMID: 34306973 Free PMC article.
Furthermore, the practitioner dependency on the amount and depth of the injected TA makes it difficult to predict the prognosis. Here, candle flame ("candlelit")-shaped TA-loaded dissolving microneedles (Candlelit-DMN) are designed and fabricated out of biocompatible and b …
Furthermore, the practitioner dependency on the amount and depth of the injected TA makes it difficult to predict the prognosis. Here, ca …
Thermally treated candle soot as a novel catalyst for hydrogen peroxide in-situ production enhancement in the bio-electro-Fenton system.
Ren Y, Yan Y, Wang Y, Zhang H, Li X. Ren Y, et al. Chemosphere. 2021 Jan;262:127839. doi: 10.1016/j.chemosphere.2020.127839. Epub 2020 Aug 8. Chemosphere. 2021. PMID: 32799145
Thermally treated candle soot (TCS) was used as a two-electron (2e) oxygen reduction reaction (ORR) catalyst to in situ produce H(2)O(2) in a bio-electro-Fenton (BEF) system. Compared with the pristine candle soot (CS), TCS showed larger Brunauer-Emmett-Teller (BET) …
Thermally treated candle soot (TCS) was used as a two-electron (2e) oxygen reduction reaction (ORR) catalyst to in situ produce H(2)O …
103 results