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Ovine fetal thymus response to lipopolysaccharide-induced chorioamnionitis and antenatal corticosteroids.
Kuypers E, Collins JJ, Jellema RK, Wolfs TG, Kemp MW, Nitsos I, Pillow JJ, Polglase GR, Newnham JP, Germeraad WT, Kallapur SG, Jobe AH, Kramer BW. Kuypers E, et al. PLoS One. 2012;7(5):e38257. doi: 10.1371/journal.pone.0038257. Epub 2012 May 31. PLoS One. 2012. PMID: 22693607 Free PMC article.
RESULTS: Intra-amniotic LPS decreased the cortico-medullary (C/M) ratio of the thymus and increased Toll-like receptor (TLR) 4 mRNA and CD3 expression indicating involution and activation of the fetal thymus. Increased TLR4 and CD3 expression persisted for 14 days but Foxp …
RESULTS: Intra-amniotic LPS decreased the cortico-medullary (C/M) ratio of the thymus and increased Toll-like receptor (TLR) 4 mRNA a …
Pulmonary and systemic endotoxin tolerance in preterm fetal sheep exposed to chorioamnionitis.
Kallapur SG, Jobe AH, Ball MK, Nitsos I, Moss TJ, Hillman NH, Newnham JP, Kramer BW. Kallapur SG, et al. J Immunol. 2007 Dec 15;179(12):8491-9. doi: 10.4049/jimmunol.179.12.8491. J Immunol. 2007. PMID: 18056396
Compared with controls, TLR4 expression did not change but IL-1R-associated kinase M expression increased in the monocytes from repeat LPS-exposed lambs. ...
Compared with controls, TLR4 expression did not change but IL-1R-associated kinase M expression increased in the monocytes from repea …