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Page 1
Adjunctive Glucocorticoid Therapy in Patients with Septic Shock.
Venkatesh B, Finfer S, Cohen J, Rajbhandari D, Arabi Y, Bellomo R, Billot L, Correa M, Glass P, Harward M, Joyce C, Li Q, McArthur C, Perner A, Rhodes A, Thompson K, Webb S, Myburgh J; ADRENAL Trial Investigators and the Australian–New Zealand Intensive Care Society Clinical Trials Group. Venkatesh B, et al. N Engl J Med. 2018 Mar 1;378(9):797-808. doi: 10.1056/NEJMoa1705835. Epub 2018 Jan 19. N Engl J Med. 2018. PMID: 29347874 Free article. Clinical Trial.
Genome-Edited T Cell Therapies.
Delhove JMKM, Qasim W. Delhove JMKM, et al. Curr Stem Cell Rep. 2017;3(2):124-136. doi: 10.1007/s40778-017-0077-5. Epub 2017 Apr 18. Curr Stem Cell Rep. 2017. PMID: 28596938 Free PMC article. Review.
Early management of adult traumatic spinal cord injury in patients with polytrauma: a consensus and clinical recommendations jointly developed by the World Society of Emergency Surgery (WSES) & the European Association of Neurosurgical Societies (EANS).
Picetti E, Demetriades AK, Catena F, Aarabi B, Abu-Zidan FM, Alves OL, Ansaloni L, Armonda RA, Badenes R, Bala M, Balogh ZJ, Barbanera A, Bertuccio A, Biffl WL, Bouzat P, Buki A, Castano-Leon AM, Cerasti D, Citerio G, Coccolini F, Coimbra R, Coniglio C, Costa F, De Iure F, Depreitere B, Fainardi E, Fehlings MJ, Gabrovsky N, Godoy DA, Gruen P, Gupta D, Hawryluk GWJ, Helbok R, Hossain I, Hutchinson PJ, Iaccarino C, Inaba K, Ivanov M, Kaprovoy S, Kirkpatrick AW, Klein S, Kolias A, Konovalov NA, Lagares A, Lippa L, Loza-Gomez A, Luoto TM, Maas AIR, Maciejczak A, Maier RV, Marklund N, Martin MJ, Melloni I, Mendoza-Lattes S, Meyfroidt G, Munari M, Napolitano LM, Okonkwo DO, Otomo Y, Papadopoulos MC, Petr O, Peul WC, Pudkrong AK, Qasim Z, Rasulo F, Reizinho C, Ringel F, Rizoli S, Rostami E, Rubiano AM, Russo E, Sarwal A, Schwab JM, Servadei F, Sharma D, Sharif S, Shiban E, Shutter L, Stahel PF, Taccone FS, Terpolilli NA, Thomé C, Toth P, Tsitsopoulos PP, Udy A, Vaccaro AR, Varon AJ, Vavilala MS, Younsi A, Zackova M, Zoerle T, Robba C. Picetti E, et al. World J Emerg Surg. 2024 Jan 18;19(1):4. doi: 10.1186/s13017-023-00525-4. World J Emerg Surg. 2024. PMID: 38238783 Free PMC article.
Moraxella canis induced sepsis from dog's lick.
Padanilam MS, Qasim M, Emery CL. Padanilam MS, et al. IDCases. 2022 Jan 10;27:e01396. doi: 10.1016/j.idcr.2022.e01396. eCollection 2022. IDCases. 2022. PMID: 35079573 Free PMC article.
We report the first description of severe disseminated infection attributed to M. canis....
We report the first description of severe disseminated infection attributed to M. canis....
Genetic mutations underlying isoniazid-resistant Mycobacterium tuberculosis in Khyber Pakhtunkhwa, Pakistan.
Khan AS, Phelan JE, Khan MT, Ali S, Qasim M, Mohammad N, Napier G, Ahmad S, Alam J, Khattak B, Campino S, Clark TG, Khan TA. Khan AS, et al. Tuberculosis (Edinb). 2023 Jan;138:102286. doi: 10.1016/j.tube.2022.102286. Epub 2022 Nov 28. Tuberculosis (Edinb). 2023. PMID: 36463715 Free article.
Isoniazid is a first-line pro-drug that requires activation through an enzyme called catalase peroxidase, but is subject to widespread resistance, driven by mutations in katG and inhA genes and other loci with compensatory effects (e.g., ahpC). Here, we used whole genome sequenci …
Isoniazid is a first-line pro-drug that requires activation through an enzyme called catalase peroxidase, but is subject to widespread resis …
Novel Mutations in MPT64 Secretory Protein of Mycobacterium tuberculosis Complex.
Muhammad N, Khan MT, Ali S, Khan TA, Khan AS, Ullah N, Higazi H, Ali S, Mohamed S, Qasim M. Muhammad N, et al. Int J Environ Res Public Health. 2023 Jan 31;20(3):2530. doi: 10.3390/ijerph20032530. Int J Environ Res Public Health. 2023. PMID: 36767896 Free PMC article.
In the current study, we aimed to find the mutation in this highly conserved protein in isolates from the Pashtun-dominant province of Pakistan. We analyzed 470 M. tuberculosis whole-genome sequences of Khyber Pakhtunkhwa Province. ...
In the current study, we aimed to find the mutation in this highly conserved protein in isolates from the Pashtun-dominant province of Pakis …
Joint Hypermobility Syndrome in Patients With Functional Dyspepsia.
Carbone F, Fikree A, Aziz Q, Tack J. Carbone F, et al. Clin Transl Gastroenterol. 2020 Nov;11(11):e00220. doi: 10.14309/ctg.0000000000000220. Clin Transl Gastroenterol. 2020. PMID: 33259162 Free PMC article.
RESULTS: A total of 62 FD patients (68% women, age 44 1.8 years, and body mass index: 21.7 0.7 kg/m) accepted to participate in the study. JHS was diagnosed in 55% of FD patients. ...
RESULTS: A total of 62 FD patients (68% women, age 44 1.8 years, and body mass index: 21.7 0.7 kg/m) accepted to participate in the s …
Artecanin of Laurus nobilis is a novel inhibitor of SARS-CoV-2 main protease with highly desirable druglikeness.
Al-Shuhaib MBS, Hashim HO, Al-Shuhaib JMB, Obayes DH. Al-Shuhaib MBS, et al. J Biomol Struct Dyn. 2023 Apr;41(6):2355-2367. doi: 10.1080/07391102.2022.2030801. Epub 2022 Jan 22. J Biomol Struct Dyn. 2023. PMID: 35067202
Main protease (M(pro)) is a critical enzyme in the life cycle of severe acute respiratory syndrome Coronavirus -2 (SARS-CoV-2). ...A total of 3392 compounds of sixty-six medicinal plants were retrieved from PubChem database and docked against M(pro). Thirty compound …
Main protease (M(pro)) is a critical enzyme in the life cycle of severe acute respiratory syndrome Coronavirus -2 (SARS-CoV-2). ...A …
Is Exercise Stress Testing Useful for Risk Stratification in Anomalous Aortic Origin of a Coronary Artery?
Qasim A, Doan TT, Dan Pham T, Reaves-O'Neal D, Sachdeva S, Mery CM, Binsalamah Z, Molossi S. Qasim A, et al. Semin Thorac Cardiovasc Surg. 2023 Winter;35(4):759-768. doi: 10.1053/j.semtcvs.2022.08.009. Epub 2022 Aug 28. Semin Thorac Cardiovasc Surg. 2023. PMID: 36041683
A (+) dobutamine-stress cardiac-magnetic-resonance-imaging (+DS-CMR) had findings of inducible-ischemia. Outcomes: (1) Differences in m-EST based on AAOCA-type; (2) Assuming DS-CMR as gold-standard for detection of inducible ischemia, determine agreement between m-E …
A (+) dobutamine-stress cardiac-magnetic-resonance-imaging (+DS-CMR) had findings of inducible-ischemia. Outcomes: (1) Differences in m
The Phenomenon of "Obesity Paradox" in Neck of Femur Fractures.
Tahir M, Ahmed N, Samejo MQA, Jamali AR. Tahir M, et al. Pak J Med Sci. 2020 Jul-Aug;36(5):1079-1083. doi: 10.12669/pjms.36.5.1952. Pak J Med Sci. 2020. PMID: 32704293 Free PMC article.
METHODS: This is prospective study conducted at Department of Orthopaedics, at a tertiary care public sector hospital in Karachi between Jan-2016 to Jan-2018. In this short follow-up study, we included the data of 490 patients, who were operated for neck of femur fr …
METHODS: This is prospective study conducted at Department of Orthopaedics, at a tertiary care public sector hospital in Karachi between …
32 results