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In vitro cytotoxic and in vivo antitumoral activities of some aminomethyl derivatives of 2,4-dihydro-3H-1,2,4-triazole-3-thiones-Evaluation of their acetylcholinesterase and carbonic anhydrase enzymes inhibition profiles.
Timur İ, Kocyigit ÜM, Dastan T, Sandal S, Ceribası AO, Taslimi P, Gulcin İ, Koparir M, Karatepe M, Çiftçi M. Timur İ, et al. J Biochem Mol Toxicol. 2018 Oct 28:e22239. doi: 10.1002/jbt.22239. Online ahead of print. J Biochem Mol Toxicol. 2018. PMID: 30368973
All the compounds had cytotoxic activities on HT29 cell lines with their IC(50) values lower than 10 M concentrations. The low IC (50) values of the compounds are M1 (3.88 M), M2 (2.18 M), M3 (4.2 M), M4 (2.58 M), M5 (2.88 M), M6 (2.37 …
All the compounds had cytotoxic activities on HT29 cell lines with their IC(50) values lower than 10 M concentrations. The low IC (50 …
Novel MASP1 mutations are associated with an expanded phenotype in 3MC1 syndrome.
Atik T, Koparir A, Bademci G, Foster J 2nd, Altunoglu U, Mutlu GY, Bowdin S, Elcioglu N, Tayfun GA, Atik SS, Ozen M, Ozkinay F, Alanay Y, Kayserili H, Thiel S, Tekin M. Atik T, et al. Orphanet J Rare Dis. 2015 Sep 30;10:128. doi: 10.1186/s13023-015-0345-3. Orphanet J Rare Dis. 2015. PMID: 26419238 Free PMC article.