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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
1963 1
1967 1
1968 1
1969 4
1970 3
1971 2
1972 1
1973 6
1974 3
1975 7
1976 6
1977 6
1978 3
1979 12
1980 7
1981 6
1982 3
1983 12
1984 4
1985 10
1986 10
1987 14
1988 21
1989 40
1990 56
1991 43
1992 51
1993 73
1994 79
1995 74
1996 75
1997 97
1998 100
1999 112
2000 163
2001 159
2002 178
2003 213
2004 224
2005 243
2006 223
2007 277
2008 340
2009 332
2010 363
2011 388
2012 459
2013 509
2014 677
2015 834
2016 895
2017 995
2018 1156
2019 1318
2020 1521
2021 1786
2022 1955
2023 1947
2024 756

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16,616 results

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Page 1
Targeting m(6)A reader YTHDF1 augments antitumour immunity and boosts anti-PD-1 efficacy in colorectal cancer.
Bao Y, Zhai J, Chen H, Wong CC, Liang C, Ding Y, Huang D, Gou H, Chen D, Pan Y, Kang W, To KF, Yu J. Bao Y, et al. Gut. 2023 Aug;72(8):1497-1509. doi: 10.1136/gutjnl-2022-328845. Epub 2023 Jan 30. Gut. 2023. PMID: 36717220 Free PMC article.
OBJECTIVE: The role of N(6)-methyladenosine (m(6)A) in tumour immune microenvironment (TIME) remains understudied. ...Importantly, targeting YTHDF1 by CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) or VNPs-siYTHDF1 boosted anti-PD1 efficacy in MSI-H CRC …
OBJECTIVE: The role of N(6)-methyladenosine (m(6)A) in tumour immune microenvironment (TIME) remains understudied. ...Importantly, ta …
METTL3 Inhibits Antitumor Immunity by Targeting m(6)A-BHLHE41-CXCL1/CXCR2 Axis to Promote Colorectal Cancer.
Chen H, Pan Y, Zhou Q, Liang C, Wong CC, Zhou Y, Huang D, Liu W, Zhai J, Gou H, Su H, Zhang X, Xu H, Wang Y, Kang W, Kei Wu WK, Yu J. Chen H, et al. Gastroenterology. 2022 Oct;163(4):891-907. doi: 10.1053/j.gastro.2022.06.024. Epub 2022 Jun 11. Gastroenterology. 2022. PMID: 35700773 Free article.
We aimed to exploit whether and how tumor-intrinsic m(6)A modification driven by methyltransferase like 3 (METTL3) can dictate the immune landscape of CRC. ...METTL3 promoted BHLHE41 expression in an m(6)A-dependent manner, which subsequently induced CXCL1 transcrip …
We aimed to exploit whether and how tumor-intrinsic m(6)A modification driven by methyltransferase like 3 (METTL3) can dictate the im …
Nam-Hong Choi, M.D., Associate Editor.
Lubowitz JH. Lubowitz JH. Arthroscopy. 2018 Jan;34(1):4. doi: 10.1016/j.arthro.2017.09.037. Arthroscopy. 2018. PMID: 29304977 No abstract available.
Alterations in the Gut Virome in Obesity and Type 2 Diabetes Mellitus.
Yang K, Niu J, Zuo T, Sun Y, Xu Z, Tang W, Liu Q, Zhang J, Ng EKW, Wong SKH, Yeoh YK, Chan PKS, Chan FKL, Miao Y, Ng SC. Yang K, et al. Gastroenterology. 2021 Oct;161(4):1257-1269.e13. doi: 10.1053/j.gastro.2021.06.056. Epub 2021 Jun 25. Gastroenterology. 2021. PMID: 34175280
METHODS: There were 128 obese subjects (body mass index 28 kg/m(2)) and 101 lean controls (body mass index 18.5 and <23 kg/m(2)) recruited from 2 regions in China (Hong Kong and Kunming). ...RESULTS: Obese subjects, especially those with T2DM (ObT2), had a …
METHODS: There were 128 obese subjects (body mass index 28 kg/m(2)) and 101 lean controls (body mass index 18.5 and <23 kg/m …
Polystyrene microplastics induce size-dependent multi-organ damage in mice: Insights into gut microbiota and fecal metabolites.
Zhang Z, Chen W, Chan H, Peng J, Zhu P, Li J, Jiang X, Zhang Z, Wang Y, Tan Z, Peng Y, Zhang S, Lin K, Yung KK. Zhang Z, et al. J Hazard Mater. 2024 Jan 5;461:132503. doi: 10.1016/j.jhazmat.2023.132503. Epub 2023 Sep 6. J Hazard Mater. 2024. PMID: 37717443
In this study, we attempted to examine the systemic toxicity of polystyrene MPs of different sizes (0.5 m MP1 and 5 m MP2) in C57BL/6 J mice. After the mice were given oral gavage of MPs for 8 consecutive weeks, histopathology and molecular biology assays, 16 S rRNA …
In this study, we attempted to examine the systemic toxicity of polystyrene MPs of different sizes (0.5 m MP1 and 5 m MP2) in …
CTX-M-producing Salmonella spp. in Hong Kong: an emerging problem.
Jin Y, Ling JM. Jin Y, et al. J Med Microbiol. 2006 Sep;55(Pt 9):1245-1250. doi: 10.1099/jmm.0.46637-0. J Med Microbiol. 2006. PMID: 16914655
Two Salmonella enterica serovar Typhimurium isolates and one S. enterica serovar Enteritidis isolate that were resistant to 4 microg cefotaxime ml-1 and produced CTX-M-type extended-spectrum beta-lactamases (ESBLs) were characterized from patients in Hong Kong durin …
Two Salmonella enterica serovar Typhimurium isolates and one S. enterica serovar Enteritidis isolate that were resistant to 4 microg cefotax …
Metabolomic phenotyping of obesity for profiling cardiovascular and ocular diseases.
Zhong P, Tan S, Zhu Z, Bulloch G, Long E, Huang W, He M, Wang W. Zhong P, et al. J Transl Med. 2023 Jun 12;21(1):384. doi: 10.1186/s12967-023-04244-x. J Transl Med. 2023. PMID: 37308902 Free PMC article.
Five obesity phenotypes were obtained by metBMI and actual BMI (actBMI): normal weight (NW, metBMI of 18.5-24.9 kg/m(2)), overweight (OW, metBMI of 25-29.9 kg/m(2)), obesity (OB, metBMI 30 kg/m(2)), overestimated (OE, metBMI-actBMI > 5 kg/m(2)), and …
Five obesity phenotypes were obtained by metBMI and actual BMI (actBMI): normal weight (NW, metBMI of 18.5-24.9 kg/m(2)), overweight …
16,616 results
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