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M. hassaballa
(11 results)?
New 1,3,4-thiadiazoles as potential anticancer agents: pro-apoptotic, cell cycle arrest, molecular modelling, and ADMET profile.
RSC Adv. 2023 May 25;13(23):15810-15825. doi: 10.1039/d3ra02716c. eCollection 2023 May 22.
RSC Adv. 2023.
PMID: 37250214
Free PMC article.
Derivatives 6b and 19 with IC(50) at less than 10 muM and with high selectivity were selected for further studies in breast cells (MCF-7). Derivative 19 arrested the breast cells at G2/M probably through inhibition of CDK1, while 6b significantly increased the sub-G1 perce …
Derivatives 6b and 19 with IC(50) at less than 10 muM and with high selectivity were selected for further studies in breast cells (MCF-7). D …
Safety and Efficacy of Epithelial Island Crosslinking in Keratoconus with Thinnest Pachymetry less than 400µ.
Omar HA, El-Agha MH, Hassaballah MA, Khalil NM.
Omar HA, et al.
Middle East Afr J Ophthalmol. 2021 Apr 30;28(1):11-17. doi: 10.4103/meajo.MEAJO_186_20. eCollection 2021 Jan-Mar.
Middle East Afr J Ophthalmol. 2021.
PMID: 34321817
Free PMC article.
PURPOSE: To evaluate the efficacy and safety of epithelial-island crosslinking (EI-CXL) in keratoconus with corneas thinner than 400 m. METHODS: Twenty-six patients (30 eyes) underwent EI-CXL (preserving the epithelium over the thinnest area), using standard protocol (3 mW …
PURPOSE: To evaluate the efficacy and safety of epithelial-island crosslinking (EI-CXL) in keratoconus with corneas thinner than 400 m …
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Rational design and eco-friendly one-pot multicomponent synthesis of novel ethylidenehydrazineylthiazol-4(5H)-ones as potential apoptotic inducers targeting wild and mutant EGFR-TK in triple negative breast cancer.
Abbass EM, Al-Karmalawy AA, Sharaky M, Khattab M, Alzahrani AYA, Hassaballah AI.
Abbass EM, et al.
Bioorg Chem. 2024 Jan;142:106936. doi: 10.1016/j.bioorg.2023.106936. Epub 2023 Oct 24.
Bioorg Chem. 2024.
PMID: 37890211
A novel series of ethylidenehydrazineylthiazol-4(5H)-ones were synthesized using various eco-friendly one-pot multicomponent synthetic techniques. The anticancer activity of compounds (4a-m) was tested against 11 cancer cell lines. While the IC(50) of all compounds was eva …
A novel series of ethylidenehydrazineylthiazol-4(5H)-ones were synthesized using various eco-friendly one-pot multicomponent synthetic techn …
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