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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1993 2
1994 1
1995 1
1996 1
1999 1
2002 2
2003 1
2004 1
2005 1
2007 1
2008 1
2009 1
2010 1
2012 1
2016 3
2021 1
2022 1
2023 1
2024 0

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21 results

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Page 1
Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells.
Green AC, Marttila P, Kiweler N, Chalkiadaki C, Wiita E, Cookson V, Lesur A, Eiden K, Bernardin F, Vallin KSA, Borhade S, Long M, Ghahe EK, Jiménez-Alonso JJ, Jemth AS, Loseva O, Mortusewicz O, Meyers M, Viry E, Johansson AI, Hodek O, Homan E, Bonagas N, Ramos L, Sandberg L, Frödin M, Moussay E, Slipicevic A, Letellier E, Paggetti J, Sørensen CS, Helleday T, Henriksson M, Meiser J. Green AC, et al. Nat Metab. 2023 Apr;5(4):642-659. doi: 10.1038/s42255-023-00771-5. Epub 2023 Apr 3. Nat Metab. 2023. PMID: 37012496 Free PMC article.
Xp38gamma/SAPK3 promotes meiotic G(2)/M transition in Xenopus oocytes and activates Cdc25C.
Perdiguero E, Pillaire MJ, Bodart JF, Hennersdorf F, Frödin M, Duesbery NS, Alonso G, Nebreda AR. Perdiguero E, et al. EMBO J. 2003 Nov 3;22(21):5746-56. doi: 10.1093/emboj/cdg559. EMBO J. 2003. PMID: 14592973 Free PMC article.
Our results indicate that phosphorylation of XCdc25C by Xp38gamma/SAPK3 is important for the meiotic G(2)/M progression of Xenopus oocytes....
Our results indicate that phosphorylation of XCdc25C by Xp38gamma/SAPK3 is important for the meiotic G(2)/M progression of Xenopus oo …
Cytotoxic potential of selected medicinal plants in northeast Brazil.
da Silva TB, Costa CO, Galvão AF, Bomfim LM, Rodrigues AC, Mota MC, Dantas AA, Dos Santos TR, Soares MB, Bezerra DP. da Silva TB, et al. BMC Complement Altern Med. 2016 Jul 8;16:199. doi: 10.1186/s12906-016-1166-1. BMC Complement Altern Med. 2016. PMID: 27391476 Free PMC article.
(Rubiaceae), Schefflera morototoni (Aubl.) Maguire, Steyerm. & Frodin (Araliaceae), Solanum paludosum Moric. (Solanaceae), Xylopia frutescens Aubl. ...RESULTS: The B. sericea, D. repens, H. bracteatus, I. purga, I. coccinea, M. piriri, O. longifolia and P. capit …
(Rubiaceae), Schefflera morototoni (Aubl.) Maguire, Steyerm. & Frodin (Araliaceae), Solanum paludosum Moric. (Solanaceae), Xylopi …
An explorative randomised phase II study of sequential chemotherapy in advanced upper gastrointestinal cancer.
Berglund A, Byström P, Johansson B, Nygren P, Frödin JE, Pedersen D, Letocha H, Glimelius B. Berglund A, et al. Med Oncol. 2010 Mar;27(1):65-72. doi: 10.1007/s12032-009-9173-4. Epub 2009 Feb 11. Med Oncol. 2010. PMID: 19212708 Clinical Trial.
Seventy-three patients with gastric (GC; n = 22), pancreatic (PC; n = 28) or biliary cancer (BC; n = 23) were randomised to start with 45 mg/m(2) docetaxel or 180 mg/m(2) irinotecan combined with 5-FU/leucovorin every 2nd week. ...
Seventy-three patients with gastric (GC; n = 22), pancreatic (PC; n = 28) or biliary cancer (BC; n = 23) were randomised to start with 45 mg …
In vitro schistosomicidal activity of some brazilian cerrado species and their isolated compounds.
Cunha NL, Uchôa CJ, Cintra LS, de Souza HC, Peixoto JA, Silva CP, Magalhães LG, Gimenez VM, Groppo M, Rodrigues V, da Silva Filho AA, Andrade E Silva ML, Cunha WR, Pauletti PM, Januário AH. Cunha NL, et al. Evid Based Complement Alternat Med. 2012;2012:173614. doi: 10.1155/2012/173614. Epub 2012 Aug 8. Evid Based Complement Alternat Med. 2012. PMID: 22924053 Free PMC article.
(Proteaceae), Struthanthus syringifolius (Mart.) (Loranthaceae), and Schefflera vinosa (Cham. & Schltdl.) Frodin (Araliaceae) are plant species from the Brazilian Cerrado whose schistosomicidal potential has not yet been described. ...Biological results indicated that …
(Proteaceae), Struthanthus syringifolius (Mart.) (Loranthaceae), and Schefflera vinosa (Cham. & Schltdl.) Frodin (Araliaceae) are …
Cytoreductive surgery and intraperitoneal chemotherapy versus systemic chemotherapy for colorectal peritoneal metastases: A randomised trial.
Cashin PH, Mahteme H, Spång N, Syk I, Frödin JE, Torkzad M, Glimelius B, Graf W. Cashin PH, et al. Eur J Cancer. 2016 Jan;53:155-62. doi: 10.1016/j.ejca.2015.09.017. Epub 2016 Jan 2. Eur J Cancer. 2016. PMID: 26751236 Clinical Trial.
METHODS: Patients deemed resectable preoperatively were randomised to surgery and intraperitoneal 5-fluorouracil 550 mg/m(2)/d for 6 d with repeated courses every month or to systemic oxaliplatin and 5-fluorouracil regimen every second week. ...
METHODS: Patients deemed resectable preoperatively were randomised to surgery and intraperitoneal 5-fluorouracil 550 mg/m(2)/d for 6 …
Influence of varying doses of granulocyte-macrophage colony-stimulating factor on pharmacokinetics and antibody-dependent cellular cytotoxicity.
Liljefors M, Nilsson B, Mellstedt H, Frödin JE. Liljefors M, et al. Cancer Immunol Immunother. 2008 Mar;57(3):379-88. doi: 10.1007/s00262-007-0377-1. Epub 2007 Aug 4. Cancer Immunol Immunother. 2008. PMID: 17676322 Clinical Trial.
Thirty-three patients received a GM-CSF dose of 200-250 microg/m(2)/day. Seventeen patients received GM-CSF doses varying between 65 and 325 microg/m(2)/day in the different treatment cycles. ...
Thirty-three patients received a GM-CSF dose of 200-250 microg/m(2)/day. Seventeen patients received GM-CSF doses varying between 65 …
Impaired mitotic progression and preimplantation lethality in mice lacking OMCG1, a new evolutionarily conserved nuclear protein.
Artus J, Vandormael-Pournin S, Frödin M, Nacerddine K, Babinet C, Cohen-Tannoudji M. Artus J, et al. Mol Cell Biol. 2005 Jul;25(14):6289-302. doi: 10.1128/MCB.25.14.6289-6302.2005. Mol Cell Biol. 2005. PMID: 15988037 Free PMC article.
Importantly, we found that Omcg1 disruption results in the lengthening of M phase rather than in a mitotic block. We show that the mitotic delay in Omcg1-/- embryos is associated with neither a dysfunction of the spindle checkpoint nor abnormal global histone modifications …
Importantly, we found that Omcg1 disruption results in the lengthening of M phase rather than in a mitotic block. We show that the mi …
Irinotecan combined with bolus 5-fluorouracil and folinic acid Nordic schedule as first-line therapy in advanced colorectal cancer.
Glimelius B, Ristamäki R, Kjaer M, Pfeiffer P, Skovsgaard T, Tveit KM, Linné T, Frödin JE, Boussard B, Oulid-Aïssa D, Pyrhönen S. Glimelius B, et al. Ann Oncol. 2002 Dec;13(12):1868-73. doi: 10.1093/annonc/mdf324. Ann Oncol. 2002. PMID: 12453854 Free article. Clinical Trial.
PATIENTS AND METHODS: Seventy-four patients with measurable disease and a WHO performance status of 2 or less were treated with irinotecan 210 mg/m(2) as a 30-90 min intravenous infusion on day 1, followed by 5-FU 500 mg/m(2) and FA 60 mg/m(2) bolus on days 1 …
PATIENTS AND METHODS: Seventy-four patients with measurable disease and a WHO performance status of 2 or less were treated with irinotecan 2 …
21 results