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The human milk component myo-inositol promotes neuronal connectivity.
Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2221413120. doi: 10.1073/pnas.2221413120. Epub 2023 Jul 11.
Proc Natl Acad Sci U S A. 2023.
PMID: 37433002
Free PMC article.
Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models.
Teuscher KB, Chowdhury S, Meyers KM, Tian J, Sai J, Van Meveren M, South TM, Sensintaffar JL, Rietz TA, Goswami S, Wang J, Grieb BC, Lorey SL, Howard GC, Liu Q, Moore WJ, Stott GM, Tansey WP, Lee T, Fesik SW.
Teuscher KB, et al.
Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2211297120. doi: 10.1073/pnas.2211297120. Epub 2022 Dec 27.
Proc Natl Acad Sci U S A. 2023.
PMID: 36574664
Free PMC article.
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Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets.
Wang MY, Dean ED, Quittner-Strom E, Zhu Y, Chowdhury KH, Zhang Z, Zhao S, Li N, Ye R, Lee Y, Zhang Y, Chen S, Yu X, Leonard DC, Poffenberger G, Von Deylen A, McCorkle SK, Schlegel A, Sloop KW, Efanov AM, Gimeno RE, Scherer PE, Powers AC, Unger RH, Holland WL.
Wang MY, et al.
Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2022142118. doi: 10.1073/pnas.2022142118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33619103
Free PMC article.
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Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).
McDonough MA, Li V, Flashman E, Chowdhury R, Mohr C, Liénard BM, Zondlo J, Oldham NJ, Clifton IJ, Lewis J, McNeill LA, Kurzeja RJ, Hewitson KS, Yang E, Jordan S, Syed RS, Schofield CJ.
McDonough MA, et al.
Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9814-9. doi: 10.1073/pnas.0601283103. Epub 2006 Jun 16.
Proc Natl Acad Sci U S A. 2006.
PMID: 16782814
Free PMC article.
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EGLN1 involvement in high-altitude adaptation revealed through genetic analysis of extreme constitution types defined in Ayurveda.
Aggarwal S, Negi S, Jha P, Singh PK, Stobdan T, Pasha MA, Ghosh S, Agrawal A; Indian Genome Variation Consortium; Prasher B, Mukerji M.
Aggarwal S, et al.
Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18961-6. doi: 10.1073/pnas.1006108107. Epub 2010 Oct 18.
Proc Natl Acad Sci U S A. 2010.
PMID: 20956315
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