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A Review on Immunological Responses to SARS-CoV-2 and Various COVID-19 Vaccine Regimens.
Upreti S, Samant M. Upreti S, et al. Pharm Res. 2022 Sep;39(9):2119-2134. doi: 10.1007/s11095-022-03323-w. Epub 2022 Jul 1. Pharm Res. 2022. PMID: 35773445 Free PMC article. Review.
So far, 7 vaccines that are already being assessed in Phase IV clinical trials are, Comirnaty/ Pfizer; Spikevax/Moderna (m RNA vaccine); Vaxzevria or Covishield; Ad26.COV2.S; Ad5-nCoV (adenoviral vector-based vaccine); CoronaVac and BBIBP-CorV (inactivated virus vaccine). …
So far, 7 vaccines that are already being assessed in Phase IV clinical trials are, Comirnaty/ Pfizer; Spikevax/Moderna (m RNA vaccin …
Maternal exposure to indoor PM2.5 and associated adverse birth outcomes in low socio-economic households, Durban, South Africa.
Shezi B, Jafta N, Asharam K, Tularam H, Jeena P, Naidoo RN. Shezi B, et al. Indoor Air. 2022 Jan;32(1):e12934. doi: 10.1111/ina.12934. Epub 2021 Sep 21. Indoor Air. 2022. PMID: 34546595
A predictive model was used to estimate PM(2.5) levels in unmeasured homes (n = 500). The mean (SD) for PM(2.5) was 37 g/m(3) (29) with a median of 28g/m(3) . The relationship between PM(2.5) exposure, birth weight, gestational age, low birth weight, and preterm del …
A predictive model was used to estimate PM(2.5) levels in unmeasured homes (n = 500). The mean (SD) for PM(2.5) was 37 g/m(3) (29) wi …
Similar Antibody Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 in Individuals Living Without and With Human Immunodeficiency Virus on Antiretroviral Therapy During the First South African Infection Wave.
Snyman J, Hwa SH, Krause R, Muema D, Reddy T, Ganga Y, Karim F, Leslie A, Sigal A, Ndung'u T; COVID-19 Mechanisms and Multi-omics at the Intersection of TB and HIV in KwaZulu-Natal (COMMIT-KZN Team). Snyman J, et al. Clin Infect Dis. 2022 Aug 24;75(1):e249-e256. doi: 10.1093/cid/ciab758. Clin Infect Dis. 2022. PMID: 34472583 Free PMC article.
METHODS: We longitudinally followed SARS-CoV-2-infected individuals in Durban, KwaZulu-Natal, South Africa, and characterized SARS-CoV-2 receptor-binding domain-specific immunoglobulin (Ig) M, IgG, and IgA weekly for 1 month and at 3 months post-diagnosis. ...
METHODS: We longitudinally followed SARS-CoV-2-infected individuals in Durban, KwaZulu-Natal, South Africa, and characterized SARS-CoV-2 rec …
Effect of short-term exposure to ambient nitrogen dioxide and particulate matter on repeated lung function measures in infancy: A South African birth cohort.
Muttoo S, Jeena PM, Röösli M, de Hoogh K, Meliefste K, Tularam H, Olin AC, Carlsen HK, Mentz G, Asharam K, Naidoo RN. Muttoo S, et al. Environ Res. 2022 Oct;213:113645. doi: 10.1016/j.envres.2022.113645. Epub 2022 Jun 11. Environ Res. 2022. PMID: 35700764
RESULTS: There were 165 infants that had lung function testing, with 82 of them having more than one test occasion. Exposure to PM(10) (mug/m(3)) resulted in a decline in tidal volume at 6 weeks [-0.4 ml (-0.9; 0.0), p = 0.065], 6 months [-0.5 ml (-1.0; 0.0), p = 0.046] an …
RESULTS: There were 165 infants that had lung function testing, with 82 of them having more than one test occasion. Exposure to PM(10) (mug/ …
Association Between Human Immunodeficiency Virus Viremia and Compromised Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Beta Variant.
Hwa SH, Snyman J, Bernstein M, Ganga Y, Cele S, Muema D, Tan CW, Khan K, Karim F, Hanekom W, Bernstein L, Kaufmann SHE, Wang LF, Ndung'u T, Sigal A; COMMIT-KZN Team. Hwa SH, et al. J Infect Dis. 2023 Jan 11;227(2):211-220. doi: 10.1093/infdis/jiac343. J Infect Dis. 2023. PMID: 35975942 Free PMC article.
Indoor air quality of low and middle income urban households in Durban, South Africa.
Jafta N, Barregard L, Jeena PM, Naidoo RN. Jafta N, et al. Environ Res. 2017 Jul;156:47-56. doi: 10.1016/j.envres.2017.03.008. Epub 2017 Mar 19. Environ Res. 2017. PMID: 28319817
RESULTS: Mean indoor concentrations of PM(10) (n=105)(,) NO(2) (n=82) and SO(2) (n=82) were 64mug/m(3) (range 6.6-241); 19mug/m(3) (range 4.5-55) and 0.6mug/m(3) (range 0.005-3.4) respectively with the distributions for all three pollutants being skewed to th …
RESULTS: Mean indoor concentrations of PM(10) (n=105)(,) NO(2) (n=82) and SO(2) (n=82) were 64mug/m(3) (range 6.6-241); 19mug/m
A Novel Sample Processing Method for Rapid Detection of Tuberculosis in the Stool of Pediatric Patients Using the Xpert MTB/RIF Assay.
Banada PP, Naidoo U, Deshpande S, Karim F, Flynn JL, O'Malley M, Jones M, Nanassy O, Jeena P, Alland D. Banada PP, et al. PLoS One. 2016 Mar 23;11(3):e0151980. doi: 10.1371/journal.pone.0151980. eCollection 2016. PLoS One. 2016. PMID: 27007974 Free PMC article.
The method was tested and optimized on stool samples spiked with known numbers of M. tuberculosis colony forming units (CFU), and stools from M. tuberculosis-infected cynomolgus macaques (Macaca fascicularis). Performance was scored on number of positive Xpert tests …
The method was tested and optimized on stool samples spiked with known numbers of M. tuberculosis colony forming units (CFU), and sto …
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