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p38γ MAPK contributes to left ventricular remodeling after pathologic stress and disinhibits calpain through phosphorylation of calpastatin.
Loonat AA, Martin ED, Sarafraz-Shekary N, Tilgner K, Hertz NT, Levin R, Shokat KM, Burlingame AL, Arabacilar P, Uddin S, Thomas M, Marber MS, Clark JE. Loonat AA, et al. FASEB J. 2019 Dec;33(12):13131-13144. doi: 10.1096/fj.201701545R. Epub 2019 Oct 22. FASEB J. 2019. PMID: 31638431 Free PMC article.
In addition, we have identified calpastatin, among other substrates, as a novel direct target of p38gamma that may contribute to the protection observed in p38gammaKO mice.-Loonat, A. A., Martin, E. D., Sarafraz-Shekary, N., Tilgner, K., Hertz, N. T., Levin, R., Shokat, K. …
In addition, we have identified calpastatin, among other substrates, as a novel direct target of p38gamma that may contribute to the protect …
Covert Tracking to Visual Stimuli in Comatose Patients With Traumatic Brain Injury.
Alkhachroum A, Aklepi G, Sarafraz A, Robayo LE, Manolovitz BM, Blandino CF, Arwari B, Sobczak E, Bass DH, Ghamasaee P, Samano D, Massad N, Kottapally M, Merenda A, Dib S, Jagid JR, Dietrich WD, Rundek T, O'Phelan K, Claassen J, Walker MF. Alkhachroum A, et al. Neurology. 2023 Sep 12;101(11):489-494. doi: 10.1212/WNL.0000000000207302. Epub 2023 Apr 19. Neurology. 2023. PMID: 37076304
Functional imaging through scattering medium via fluorescence speckle demixing and localization.
Soldevila F, Moretti C, Nöbauer T, Sarafraz H, Vaziri A, Gigan S. Soldevila F, et al. Opt Express. 2023 Jun 19;31(13):21107-21117. doi: 10.1364/OE.487768. Opt Express. 2023. PMID: 37381218 Free article.
We test our approach by imaging the temporal activity of large groups of fluorescent sources behind different scattering phantoms mimicking biological tissues, and through a brain slice with a thickness of 200 m....
We test our approach by imaging the temporal activity of large groups of fluorescent sources behind different scattering phantoms mimicking …
Modelling of mass transport and distribution of aptamer in blood-brain barrier for tumour therapy and cancer treatment.
Sarafraz M, Nakhjavani M, Shigdar S, Christo FC, Rolfe B. Sarafraz M, et al. Eur J Pharm Biopharm. 2022 Apr;173:121-131. doi: 10.1016/j.ejpb.2022.03.004. Epub 2022 Mar 10. Eur J Pharm Biopharm. 2022. PMID: 35283304
To get a better understanding of this phenomenon, in the present article, a mathematical model based on the finite element method was developed accounting for the fluid flow and mass transport of the aptamer molecule inside an 8 m capillary vessel across a 14 m bloo …
To get a better understanding of this phenomenon, in the present article, a mathematical model based on the finite element method was develo …
Molecular evaluation of pvdhfr and pvmdr-1 mutants in Plasmodium vivax isolates after treatment with sulfadoxine/pyrimethamine and chloroquine in Iran during 2001-2016.
Parsaei M, Raeisi A, Spotin A, Shahbazi A, Mahami-Oskouei M, Hazratian T, Khorashad AS, Zaman J, Bazmani A, Sarafraz S. Parsaei M, et al. Infect Genet Evol. 2018 Oct;64:70-75. doi: 10.1016/j.meegid.2018.06.021. Epub 2018 Jun 19. Infect Genet Evol. 2018. PMID: 29929007
The genomic DNA was extracted and examined using nested polymerase chain reaction-(PCR) and sequencing. Mutations were detected in pvdhfr codons P33L (21.2%), T61 M (25%), S93H (3.9%), and S117 T (1.9%) and 5 isolates showed double mutations (33 L/61 M, 7.7%; 33 L/1 …
The genomic DNA was extracted and examined using nested polymerase chain reaction-(PCR) and sequencing. Mutations were detected in pvdhfr co …
Comparative study of energy consumption, kinetic, and performance between conventional and baffled photocatalytic reactor (BPCR) to ofloxacin photo-degradation.
Karimi P, Sadani M, Azarpira H, Rasolevandi T, Sarafraz M. Karimi P, et al. Environ Sci Pollut Res Int. 2022 Sep;29(43):64914-64923. doi: 10.1007/s11356-022-20066-8. Epub 2022 Apr 27. Environ Sci Pollut Res Int. 2022. PMID: 35476267
Also, kinetic model E(Eo) declines from 15.23 to 8.61 and from 13.31 to 5.37 kWh m(-3) in conventional and BPCR, respectively. Total cost of the system (TCS) decreases from 7.31 to 2.16 $ in conventional reactor and 4.57 to 0.55 $ in PCBR reactor. ...
Also, kinetic model E(Eo) declines from 15.23 to 8.61 and from 13.31 to 5.37 kWh m(-3) in conventional and BPCR, respectively. Total …