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Force decay of polyethylene terephthalate glycol aligner materials during simulation of typical clinical loading/unloading scenarios.
Elkholy F, Schmidt S, Schmidt F, Amirkhani M, Lapatki BG. Elkholy F, et al. J Orofac Orthop. 2023 May;84(3):189-201. doi: 10.1007/s00056-021-00364-5. Epub 2021 Dec 9. J Orofac Orthop. 2023. PMID: 34882259 Free PMC article.
RESULTS: A very large decay in force for the PET-G specimens could already be observed after the first loading period, with significantly different residual force values of 24, 20, and 21% recorded for the 12 h/12 h, 18 h/6 h, and 23 h/1 h
RESULTS: A very large decay in force for the PET-G specimens could already be observed after the first loading period, with significantly di …
DCZ0415, a small-molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β-catenin pathway in colorectal cancer.
Agarwal S, Afaq F, Bajpai P, Kim HG, Elkholy A, Behring M, Chandrashekar DS, Diffalha SA, Khushman M, Sugandha SP, Varambally S, Manne U. Agarwal S, et al. Mol Oncol. 2022 Apr;16(8):1728-1745. doi: 10.1002/1878-0261.13201. Epub 2022 Mar 7. Mol Oncol. 2022. PMID: 35194944 Free PMC article.
The treatment of CRC cells with DCZ0415 resulted in decreased cell proliferation, induced cell cycle arrest in the G2-M phase and increased apoptosis. DCZ0415 diminished xenograft tumour growth and metastasis of CRC in immunocompromised mice. ...
The treatment of CRC cells with DCZ0415 resulted in decreased cell proliferation, induced cell cycle arrest in the G2-M phase and inc …
Exposure to polystyrene microplastic beads causes sex-specific toxic effects in the model insect Drosophila melanogaster.
El Kholy S, Al Naggar Y. El Kholy S, et al. Sci Rep. 2023 Jan 5;13(1):204. doi: 10.1038/s41598-022-27284-7. Sci Rep. 2023. PMID: 36604504 Free PMC article.
To fill this gab, we conducted a series of experiments using Drosophila as a model organism to understand whether exposure to different concentrations (0.005, 0.05, 0.5 g/ml) of polystyrene microplastics (PS-MPs) beads (2 m in size) can impact flies feeding activity, diges …
To fill this gab, we conducted a series of experiments using Drosophila as a model organism to understand whether exposure to different conc …
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies.
Ferrari M, Righi M, Baldan V, Wawrzyniecka P, Bulek A, Kinna A, Ma B, Bughda R, Akbar Z, Srivastava S, Gannon I, Robson M, Sillibourne J, Jha R, El-Kholy M, Amin OM, Kokalaki E, Banani MA, Hussain R, Day W, Lim WC, Ghongane P, Hopkins JR, Jungherz D, Herling M, Welin M, Surade S, Dyson M, McCafferty J, Logan D, Cordoba S, Thomas S, Sewell A, Maciocia P, Onuoha S, Pule M. Ferrari M, et al. Nat Commun. 2024 Feb 21;15(1):1583. doi: 10.1038/s41467-024-45854-3. Nat Commun. 2024. PMID: 38383515 Free PMC article.
Walnut Kernel Oil and Defatted Extracts Enhance Mesenchymal Stem Cell Stemness and Delay Senescence.
Elsied MA, Sharawi ZW, Al-Amrah H, Hegazy RA, Mohamed AE, Saleh RM, El-Kholy SS, Farrag FA, Fayed MH, El-Magd MA. Elsied MA, et al. Molecules. 2023 Aug 28;28(17):6281. doi: 10.3390/molecules28176281. Molecules. 2023. PMID: 37687109 Free PMC article.
Premature senescence and inflammation were induced in BM-MSCs using H(2)O(2) and LPS, respectively. Phytochemical constituents of WKO and WKD extracts were detected by HPLC. ...WKO and WKD extracts improved rat BM-MSC stemness, as evidenced by (1) increased cell viability, …
Premature senescence and inflammation were induced in BM-MSCs using H(2)O(2) and LPS, respectively. Phytochemical constituents of WKO …
Genomic analysis of the emergence of drug-resistant strains of Mycobacterium tuberculosis in the Middle East.
Alyamani EJ, Marcus SA, Ramirez-Busby SM, Hansen C, Rashid J, El-Kholy A, Spalink D, Valafar F, Almehdar HA, A Jiman-Fatani A, Khiyami MA, Talaat AM. Alyamani EJ, et al. Sci Rep. 2019 Mar 14;9(1):4474. doi: 10.1038/s41598-019-41162-9. Sci Rep. 2019. PMID: 30872748 Free PMC article.
We sought to examine the genomic variations among recently isolated strains of M. tuberculosis in two closely related countries with different population demography in the Middle East. Clinical isolates of M. tuberculosis from both Egypt and Saudi Arabia were subjec …
We sought to examine the genomic variations among recently isolated strains of M. tuberculosis in two closely related countries with …
Processing and characterization of antimicrobial bioplastic films based on green microalgae Scenedesmus obliquus extract-loaded polyurethane.
Abdo SM, Youssef M, El Nagar I, Mohamed HE, El-Kholy SA, Youssef AM. Abdo SM, et al. Int J Biol Macromol. 2024 Feb;257(Pt 2):128711. doi: 10.1016/j.ijbiomac.2023.128711. Epub 2023 Dec 12. Int J Biol Macromol. 2024. PMID: 38096929
The bioplastic films were characterized using water vapor transmission rate measurements and scanning electron microscopy (SEM). The WVTR of pure PU was 193.37 g/m(2). day, while the values of algae/PU films were 129.74, 122.56, and 99.75 g/m(2).day. ...The antimicr …
The bioplastic films were characterized using water vapor transmission rate measurements and scanning electron microscopy (SEM). The WVTR of …
Synergistic Influence of Arbuscular mycorrhizal Fungi Inoculation with Nanoparticle Foliar Application Enhances Chili (Capsicum annuum L.) Antioxidant Enzymes, Anatomical Characteristics, and Productivity under Cold-Stress Conditions.
Sayed EG, Desoukey SF, Desouky AF, Farag MF, El-Kholy RI, Azoz SN. Sayed EG, et al. Plants (Basel). 2024 Feb 14;13(4):517. doi: 10.3390/plants13040517. Plants (Basel). 2024. PMID: 38498503 Free PMC article.
Additionally, the combination of AMF and a mixture of nanoparticles (ZnO-NPs + Se-NPs) significantly increased the total marketable yield by 95.8% and 94.7% compared to the control, which recorded values of 2.4 and 1.9 kg m(-2) in the 2021 and 2022 seasons, respectively. F …
Additionally, the combination of AMF and a mixture of nanoparticles (ZnO-NPs + Se-NPs) significantly increased the total marketable yield by …
12 results