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Pairwise combinations of chemical compounds that delay yeast chronological aging through different signaling pathways display synergistic effects on the extent of aging delay.
Dakik P, McAuley M, Chancharoen M, Mitrofanova D, Lozano Rodriguez ME, Baratang Junio JA, Lutchman V, Cortes B, Simard É, Titorenko VI. Dakik P, et al. Among authors: mcauley m. Oncotarget. 2019 Jan 8;10(3):313-338. doi: 10.18632/oncotarget.26553. eCollection 2019 Jan 8. Oncotarget. 2019. PMID: 30719227 Free PMC article.
Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes.
Lutchman V, Medkour Y, Samson E, Arlia-Ciommo A, Dakik P, Cortes B, Feldman R, Mohtashami S, McAuley M, Chancharoen M, Rukundo B, Simard É, Titorenko VI. Lutchman V, et al. Among authors: mcauley m. Oncotarget. 2016 Mar 29;7(13):16542-66. doi: 10.18632/oncotarget.7665. Oncotarget. 2016. PMID: 26918729 Free PMC article.
Specific changes in mitochondrial lipidome alter mitochondrial proteome and increase the geroprotective efficiency of lithocholic acid in chronologically aging yeast.
Leonov A, Arlia-Ciommo A, Bourque SD, Koupaki O, Kyryakov P, Dakik P, McAuley M, Medkour Y, Mohammad K, Di Maulo T, Titorenko VI. Leonov A, et al. Among authors: mcauley m. Oncotarget. 2017 May 9;8(19):30672-30691. doi: 10.18632/oncotarget.16766. Oncotarget. 2017. PMID: 28410198 Free PMC article.