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Donepezil Derivatives Targeting Amyloid-β Cascade in Alzheimer's Disease.
Mezeiova E, Chalupova K, Nepovimova E, Gorecki L, Prchal L, Malinak D, Kuca K, Soukup O, Korabecny J. Mezeiova E, et al. Among authors: gorecki l. Curr Alzheimer Res. 2019;16(9):772-800. doi: 10.2174/1567205016666190228122956. Curr Alzheimer Res. 2019. PMID: 30819078 Review.
Profiling donepezil template into multipotent hybrids with antioxidant properties.
Mezeiova E, Spilovska K, Nepovimova E, Gorecki L, Soukup O, Dolezal R, Malinak D, Janockova J, Jun D, Kuca K, Korabecny J. Mezeiova E, et al. Among authors: gorecki l. J Enzyme Inhib Med Chem. 2018 Dec;33(1):583-606. doi: 10.1080/14756366.2018.1443326. J Enzyme Inhib Med Chem. 2018. PMID: 29529892 Free PMC article. Review.
Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease.
Gorecki L, Uliassi E, Bartolini M, Janockova J, Hrabinova M, Hepnarova V, Prchal L, Muckova L, Pejchal J, Karasova JZ, Mezeiova E, Benkova M, Kobrlova T, Soukup O, Petralla S, Monti B, Korabecny J, Bolognesi ML. Gorecki L, et al. ACS Chem Neurosci. 2021 May 5;12(9):1698-1715. doi: 10.1021/acschemneuro.1c00184. Epub 2021 Apr 14. ACS Chem Neurosci. 2021. PMID: 33852284
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase.
Gorecki L, Hepnarova V, Karasova JZ, Hrabinova M, Courageux C, Dias J, Kucera T, Kobrlova T, Muckova L, Prchal L, Malinak D, Jun D, Musilek K, Worek F, Nachon F, Soukup O, Korabecny J. Gorecki L, et al. Arch Toxicol. 2021 Mar;95(3):985-1001. doi: 10.1007/s00204-021-02981-w. Epub 2021 Jan 31. Arch Toxicol. 2021. PMID: 33517499
Huprine Y - Tryptophan heterodimers with potential implication to Alzheimer's disease treatment.
Mezeiova E, Hrabinova M, Hepnarova V, Jun D, Janockova J, Muckova L, Prchal L, Kristofikova Z, Kucera T, Gorecki L, Chalupova K, Kunes J, Hroudova J, Soukup O, Korabecny J. Mezeiova E, et al. Among authors: gorecki l. Bioorg Med Chem Lett. 2021 Jul 1;43:128100. doi: 10.1016/j.bmcl.2021.128100. Epub 2021 May 10. Bioorg Med Chem Lett. 2021. PMID: 33984470
26 results