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Page 1
NUAK1 promotes organ fibrosis via YAP and TGF-β/SMAD signaling.
Zhang T, He X, Caldwell L, Goru SK, Ulloa Severino L, Tolosa MF, Misra PS, McEvoy CM, Christova T, Liu Y, Atin C, Zhang J, Hu C, Vukosa N, Chen X, Krizova A, Kirpalani A, Gregorieff A, Ni R, Chan K, Gill MK, Attisano L, Wrana JL, Yuen DA. Zhang T, et al. Among authors: ulloa severino l. Sci Transl Med. 2022 Mar 23;14(637):eaaz4028. doi: 10.1126/scitranslmed.aaz4028. Epub 2022 Mar 23. Sci Transl Med. 2022. PMID: 35320001
Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis.
He X, Tolosa MF, Zhang T, Goru SK, Ulloa Severino L, Misra PS, McEvoy CM, Caldwell L, Szeto SG, Gao F, Chen X, Atin C, Ki V, Vukosa N, Hu C, Zhang J, Yip C, Krizova A, Wrana JL, Yuen DA. He X, et al. Among authors: ulloa severino l. JCI Insight. 2022 Feb 22;7(4):e146243. doi: 10.1172/jci.insight.146243. JCI Insight. 2022. PMID: 35191398 Free PMC article.
Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome.
Capaci V, Bascetta L, Fantuz M, Beznoussenko GV, Sommaggio R, Cancila V, Bisso A, Campaner E, Mironov AA, Wiśniewski JR, Ulloa Severino L, Scaini D, Bossi F, Lees J, Alon N, Brunga L, Malkin D, Piazza S, Collavin L, Rosato A, Bicciato S, Tripodo C, Mantovani F, Del Sal G. Capaci V, et al. Among authors: ulloa severino l. Nat Commun. 2020 Aug 7;11(1):3945. doi: 10.1038/s41467-020-17596-5. Nat Commun. 2020. PMID: 32770028 Free PMC article.
Mechanical cues control mutant p53 stability through a mevalonate-RhoA axis.
Ingallina E, Sorrentino G, Bertolio R, Lisek K, Zannini A, Azzolin L, Severino LU, Scaini D, Mano M, Mantovani F, Rosato A, Bicciato S, Piccolo S, Del Sal G. Ingallina E, et al. Among authors: severino lu. Nat Cell Biol. 2018 Jan;20(1):28-35. doi: 10.1038/s41556-017-0009-8. Epub 2017 Dec 18. Nat Cell Biol. 2018. PMID: 29255172 Free PMC article.
In vitro myogenesis induced by human recombinant elastin-like proteins.
D'Andrea P, Scaini D, Ulloa Severino L, Borelli V, Passamonti S, Lorenzon P, Bandiera A. D'Andrea P, et al. Among authors: ulloa severino l. Biomaterials. 2015 Oct;67:240-53. doi: 10.1016/j.biomaterials.2015.07.041. Epub 2015 Jul 23. Biomaterials. 2015. PMID: 26231915