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LogD-based modelling and ΔlogD as a proxy for pH-dependent action of ionizable chemicals reveal the relevance of both neutral and ionic species for fish embryotoxicity and possess great potential for practical application in the regulation of chemicals.
Köhler HR, Gräff T, Schweizer M, Blumhardt J, Burkhardt J, Ehmann L, Hebel J, Heid C, Kundy L, Kuttler J, Malusova M, Moroff FM, Schlösinger AF, Schulze-Berge P, Panagopoulou EI, Damalas DE, Thomaidis NS, Triebskorn R, Maletzki D, Kühnen U, von der Ohe PC. Köhler HR, et al. Among authors: ehmann l. Water Res. 2023 May 15;235:119864. doi: 10.1016/j.watres.2023.119864. Epub 2023 Mar 14. Water Res. 2023. PMID: 36944304 Free article.
Linezolid Concentrations in Plasma and Subcutaneous Tissue are Reduced in Obese Patients, Resulting in a Higher Risk of Underdosing in Critically Ill Patients: A Controlled Clinical Pharmacokinetic Study.
Simon P, Busse D, Petroff D, Dorn C, Ehmann L, Hochstädt S, Girrbach F, Dietrich A, Zeitlinger M, Kees F, Kloft C, Wrigge H. Simon P, et al. Among authors: ehmann l. J Clin Med. 2020 Apr 9;9(4):1067. doi: 10.3390/jcm9041067. J Clin Med. 2020. PMID: 32283731 Free PMC article.