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Year Number of Results
1948 1
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1974 5
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1976 4
1977 2
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1979 5
1980 4
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1982 2
1983 3
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1987 3
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1990 9
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2004 23
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2007 29
2008 28
2009 27
2010 40
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1,209 results

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The following term was not found in PubMed: Linvolak
Page 1
[Obstructive shock].
Pich H, Heller AR. Pich H, et al. Anaesthesist. 2015 May;64(5):403-19. doi: 10.1007/s00101-015-0031-9. Anaesthesist. 2015. PMID: 25994928 Review. German.
PICH Activates Cyclin A1 Transcription to Drive S-Phase Progression and Chemoresistance in Gastric Cancer.
Ye H, Shi W, Yang J, Wang L, Jiang X, Zhao H, Qin L, Qin J, Li L, Cai W, Guan J, Yang H, Zhou H, Yu Z, Sun H, Jiao Z. Ye H, et al. Cancer Res. 2023 Nov 15;83(22):3767-3782. doi: 10.1158/0008-5472.CAN-23-1331. Cancer Res. 2023. PMID: 37646571
Here, we identified the SNF2 protein Polo-like kinase 1-interacting checkpoint helicase (PICH) as a predictor of 5-FU chemosensitivity and characterized a transcriptional function of PICH distinct from its role in chromosome separation. ...Binding of the PICH
Here, we identified the SNF2 protein Polo-like kinase 1-interacting checkpoint helicase (PICH) as a predictor of 5-FU chemosensitivit …
Break-induced replication orchestrates resection-dependent template switching.
Zhang T, Rawal Y, Jiang H, Kwon Y, Sung P, Greenberg RA. Zhang T, et al. Nature. 2023 Jul;619(7968):201-208. doi: 10.1038/s41586-023-06177-3. Epub 2023 Jun 14. Nature. 2023. PMID: 37316655 Free PMC article.
Here we combine synchronous double-strand break induction with proteomics of isolated chromatin segments (PICh) to capture the telomeric DNA damage response proteome during BITS(1,6). ...
Here we combine synchronous double-strand break induction with proteomics of isolated chromatin segments (PICh) to capture the telome …
PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response.
Geng X, Zhang C, Li M, Wang J, Ji F, Feng H, Xing M, Li F, Zhang L, Li W, Chen Z, Hickson ID, Shen H, Ying S. Geng X, et al. Adv Sci (Weinh). 2022 Mar;9(7):e2103837. doi: 10.1002/advs.202103837. Epub 2022 Jan 17. Adv Sci (Weinh). 2022. PMID: 35037428 Free PMC article.
Previous studies show PICH deficiency-induced embryonic lethality in mice. However, the function of PICH that is required to suppress embryonic lethality in PICH-deficient mammals remains to be determined. Previous clinical studies suggest a link between P
Previous studies show PICH deficiency-induced embryonic lethality in mice. However, the function of PICH that is required to s …
FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics.
Stok C, Tsaridou S, van den Tempel N, Everts M, Wierenga E, Bakker FJ, Kok Y, Alves IT, Jae LT, Raas MWD, Huis In 't Veld PJ, de Boer HR, Bhattacharya A, Karanika E, Warner H, Chen M, van de Kooij B, Dessapt J, Ter Morsche L, Perepelkina P, Fradet-Turcotte A, Guryev V, Tromer EC, Chan KL, Fehrmann RSN, van Vugt MATM. Stok C, et al. Cell Rep. 2023 Jul 25;42(7):112668. doi: 10.1016/j.celrep.2023.112668. Epub 2023 Jun 21. Cell Rep. 2023. PMID: 37347663 Free article.
Persistent joint molecules give rise to ultrafine DNA bridges (UFBs) in mitosis, compromising sister chromatid separation. The DNA translocase PICH (ERCC6L) has a central role in UFB resolution. A genome-wide loss-of-function screen is performed to identify the genetic con …
Persistent joint molecules give rise to ultrafine DNA bridges (UFBs) in mitosis, compromising sister chromatid separation. The DNA transloca …
PICH acts as a force-dependent nucleosome remodeler.
Spakman D, Clement TVM, Biebricher AS, King GA, Singh MI, Hickson ID, Peterman EJG, Wuite GJL. Spakman D, et al. Nat Commun. 2022 Nov 25;13(1):7277. doi: 10.1038/s41467-022-35040-8. Nat Commun. 2022. PMID: 36433994 Free PMC article.
Applying a combination of dual-trap optical tweezers and fluorescence imaging of PICH and histones bound to a nucleosome-array construct, we show that PICH is a tension- and ATP-dependent nucleosome remodeler that facilitates nucleosome unwrapping and then subsequen …
Applying a combination of dual-trap optical tweezers and fluorescence imaging of PICH and histones bound to a nucleosome-array constr …
PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis.
Nielsen CF, Huttner D, Bizard AH, Hirano S, Li TN, Palmai-Pallag T, Bjerregaard VA, Liu Y, Nigg EA, Wang LH, Hickson ID. Nielsen CF, et al. Nat Commun. 2015 Dec 8;6:8962. doi: 10.1038/ncomms9962. Nat Commun. 2015. PMID: 26643143 Free PMC article.
PICH is a SNF2 family DNA translocase that binds to ultra-fine DNA bridges (UFBs) in mitosis. ...PICH co-localizes with Topo IIalpha on UFBs and at the ribosomal DNA locus, and the timely resolution of both structures depends on the ATPase activity of PICH. .
PICH is a SNF2 family DNA translocase that binds to ultra-fine DNA bridges (UFBs) in mitosis. ...PICH co-localizes with Topo I
The ZATT-TOP2A-PICH Axis Drives Extensive Replication Fork Reversal to Promote Genome Stability.
Tian T, Bu M, Chen X, Ding L, Yang Y, Han J, Feng XH, Xu P, Liu T, Ying S, Lei Y, Li Q, Huang J. Tian T, et al. Mol Cell. 2021 Jan 7;81(1):198-211.e6. doi: 10.1016/j.molcel.2020.11.007. Epub 2020 Dec 8. Mol Cell. 2021. PMID: 33296677 Free article.
This is accompanied by an increase in TOP2A SUMOylation mediated by the SUMO E3 ligase ZATT and followed by recruitment of a SUMO-targeted DNA translocase, PICH. Disruption of the ZATT-TOP2A-PICH axis results in accumulation of partially reversed forks and enhanced …
This is accompanied by an increase in TOP2A SUMOylation mediated by the SUMO E3 ligase ZATT and followed by recruitment of a SUMO-targeted D …
PICH: a DNA translocase specially adapted for processing anaphase bridge DNA.
Biebricher A, Hirano S, Enzlin JH, Wiechens N, Streicher WW, Huttner D, Wang LH, Nigg EA, Owen-Hughes T, Liu Y, Peterman E, Wuite GJL, Hickson ID. Biebricher A, et al. Mol Cell. 2013 Sep 12;51(5):691-701. doi: 10.1016/j.molcel.2013.07.016. Epub 2013 Aug 22. Mol Cell. 2013. PMID: 23973328 Free PMC article.
However, very little is known about the function of PICH or how it is recruited to UFBs. Using a combination of microfluidics, fluorescence microscopy, and optical tweezers, we have defined the properties of PICH in an in vitro model of an anaphase bridge. ...PIC
However, very little is known about the function of PICH or how it is recruited to UFBs. Using a combination of microfluidics, fluore …
1,209 results