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Certolizumab pegol, abatacept, tocilizumab or active conventional treatment in early rheumatoid arthritis: 48-week clinical and radiographic results of the investigator-initiated randomised controlled NORD-STAR trial.
Østergaard M, van Vollenhoven RF, Rudin A, Hetland ML, Heiberg MS, Nordström DC, Nurmohamed MT, Gudbjornsson B, Ørnbjerg LM, Bøyesen P, Lend K, Hørslev-Petersen K, Uhlig T, Sokka T, Grondal G, Krabbe S, Lindqvist J, Gjertsson I, Glinatsi D, Kapetanovic MC, Aga AB, Faustini F, Parmanne P, Lorenzen T, Giovanni C, Back J, Hendricks O, Vedder D, Rannio T, Grenholm E, Ljoså MK, Brodin E, Lindegaard H, Söderbergh A, Rizk M, Kastbom A, Larsson P, Uhrenholt L, Just SA, Stevens DJ, Bay Laurbjerg T, Bakland G, Olsen IC, Haavardsholm EA, Lampa J; NORD-STAR study group. Østergaard M, et al. Ann Rheum Dis. 2023 Oct;82(10):1286-1295. doi: 10.1136/ard-2023-224116. Epub 2023 Jul 9. Ann Rheum Dis. 2023. PMID: 37423647 Clinical Trial.
BACKGROUND: The optimal first-line treatment in early rheumatoid arthritis (RA) is debated. We compared clinical and radiographic outcomes of active conventional therapy with each of three biological treatments with different modes of action. ...
BACKGROUND: The optimal first-line treatment in early rheumatoid arthritis (RA) is debated. We compared clinical and radiographic out …
Lung ultrasound findings in hospitalized COVID-19 patients in relation to venous thromboembolic events: the ECHOVID-19 study.
Skaarup KG, Lassen MCH, Espersen C, Lind JN, Johansen ND, Sengeløv M, Alhakak AS, Nielsen AB, Ravnkilde K, Hauser R, Schöps LB, Holt E, Bundgaard H, Hassager C, Jabbari R, Carlsen J, Kirk O, Bodtger U, Lindholm MG, Wiese L, Kristiansen OP, Walsted ES, Nielsen OW, Lindegaard B, Tønder N, Jeschke KN, Ulrik CS, Lamberts M, Sivapalan P, Pallisgaard J, Gislason G, Iversen K, Jensen JUS, Schou M, Skaarup SH, Platz E, Biering-Sørensen T. Skaarup KG, et al. J Ultrasound. 2022 Sep;25(3):457-467. doi: 10.1007/s40477-021-00605-8. Epub 2021 Jul 2. J Ultrasound. 2022. PMID: 34213740 Free PMC article.
All patients underwent 8-zone LUS, and all ultrasound images were analyzed off-line blinded. Several LUS findings were investigated (total number of B-lines, B-line score, and LUS-scores). ...The B-line score and LUS-score remained significantly associated wi …
All patients underwent 8-zone LUS, and all ultrasound images were analyzed off-line blinded. Several LUS findings were investigated ( …
Single line source with and without vaginal loading and the impact on target coverage and organ at risk doses for cervix cancer Stages IB, II, and IIIB: treatment planning simulation in patients treated with MRI-guided adaptive brachytherapy in a multicentre study (EMBRACE).
Nkiwane KS, Pötter R, Tanderup K, Federico M, Lindegaard JC, Kirisits C. Nkiwane KS, et al. Brachytherapy. 2013 Jul-Aug;12(4):317-23. doi: 10.1016/j.brachy.2012.11.001. Epub 2013 Mar 7. Brachytherapy. 2013. PMID: 23474352
A 30-year experience in using oral methotrexate as initial treatment for gestational trophoblastic neoplasia regardless of risk group.
Faaborg L, Niemann I, Ostenfeld EB, Hansen ES, Sunde L, Lindegaard JC. Faaborg L, et al. Acta Oncol. 2016;55(2):234-9. doi: 10.3109/0284186X.2015.1059486. Epub 2015 Jun 24. Acta Oncol. 2016. PMID: 26106854
Data were obtained from medical records, using histopathology and human choriogonadotropin (hCG) to verify the diagnosis. All patients received oral MTX as first-line chemotherapy. Second- and third-line chemotherapy was given according to response. RESULTS: Sixty-f …
Data were obtained from medical records, using histopathology and human choriogonadotropin (hCG) to verify the diagnosis. All patients recei …
Experiences of internet-based cognitive behavioural therapy for depression and anxiety among Arabic-speaking individuals in Sweden: a qualitative study.
Lindegaard T, Kashoush F, Holm S, Halaj A, Berg M, Andersson G. Lindegaard T, et al. BMC Psychiatry. 2021 Jun 3;21(1):288. doi: 10.1186/s12888-021-03297-w. BMC Psychiatry. 2021. PMID: 34082745 Free PMC article.
CONCLUSIONS: The findings in the present study are largely in line with previous qualitative research studies on ICBT participants. ...
CONCLUSIONS: The findings in the present study are largely in line with previous qualitative research studies on ICBT participants. . …
Social relations and presence of others predict bystander intervention: Evidence from violent incidents captured on CCTV.
Liebst LS, Philpot R, Bernasco W, Dausel KL, Ejbye-Ernst P, Nicolaisen MH, Lindegaard MR. Liebst LS, et al. Aggress Behav. 2019 Nov;45(6):598-609. doi: 10.1002/ab.21853. Epub 2019 Jul 29. Aggress Behav. 2019. PMID: 31359450 Free PMC article.
However, recent meta-analytical evidence questions whether this effect generalizes to violent emergencies. Besides the number of bystanders present, an alternative line of research suggests that pre-existing social relations between bystanders and conflict participants are …
However, recent meta-analytical evidence questions whether this effect generalizes to violent emergencies. Besides the number of bystanders …
Splice-Switching Antisense Oligonucleotides Correct Phenylalanine Hydroxylase Exon 11 Skipping Defects and Rescue Enzyme Activity in Phenylketonuria.
Martínez-Pizarro A, Álvarez M, Dembic M, Lindegaard CA, Castro M, Richard E, Andresen BS, Desviat LR. Martínez-Pizarro A, et al. Nucleic Acid Ther. 2024 Apr 9. doi: 10.1089/nat.2024.0014. Online ahead of print. Nucleic Acid Ther. 2024. PMID: 38591802
To examine the functional rescue induced by the SSOs, we generated a hepatoma cell model with variant c.1199+17G>A using CRISPR/Cas9. The edited cell line reproduces the exon 11 skipping pattern observed from minigenes, leading to reduced PAH protein levels and activity …
To examine the functional rescue induced by the SSOs, we generated a hepatoma cell model with variant c.1199+17G>A using CRISPR/Cas9. The …
Risk Factors for Pelvic Insufficiency Fractures in Locally Advanced Cervical Cancer Following Intensity Modulated Radiation Therapy.
Ramlov A, Pedersen EM, Røhl L, Worm E, Fokdal L, Lindegaard JC, Tanderup K. Ramlov A, et al. Int J Radiat Oncol Biol Phys. 2017 Apr 1;97(5):1032-1039. doi: 10.1016/j.ijrobp.2017.01.026. Epub 2017 Mar 15. Int J Radiat Oncol Biol Phys. 2017. PMID: 28332986
Follow-up magnetic resonance imaging was performed routinely at 3 and 12 months after the end of treatment or based on clinical indication. PIF was defined as a fracture line with or without sclerotic changes in the pelvic bones. D(50%) and V(55Gy) were calculated for the …
Follow-up magnetic resonance imaging was performed routinely at 3 and 12 months after the end of treatment or based on clinical indication. …
Evaluating the Efficacy of Internet-Delivered Cognitive Behavioral Therapy Blended With Synchronous Chat Sessions to Treat Adolescent Depression: Randomized Controlled Trial.
Topooco N, Byléhn S, Dahlström Nysäter E, Holmlund J, Lindegaard J, Johansson S, Åberg L, Bergman Nordgren L, Zetterqvist M, Andersson G. Topooco N, et al. J Med Internet Res. 2019 Nov 1;21(11):e13393. doi: 10.2196/13393. J Med Internet Res. 2019. PMID: 31682572 Free PMC article. Clinical Trial.
A significant between-group effect was observed in the secondary depression outcome (P=.003); clinically significant improvement was found in 46% (16/35) of ICBT participants compared with 11% (4/35) in the control group (P=.001). CONCLUSIONS: The results are in line with …
A significant between-group effect was observed in the secondary depression outcome (P=.003); clinically significant improvement was found i …
16 results