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Year Number of Results
2016 2
2017 1
2018 2
2019 2
2020 2
2021 1
2022 3
2024 0

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13 results

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Page 1
Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation.
Cristancho Ortiz CJ, de Freitas Silva M, Pruccoli L, Fonseca Nadur N, de Azevedo LL, Kümmerle AE, Guedes IA, Dardenne LE, Leomil Coelho LF, Guimarães MJ, da Silva FMR, Castro N, Gontijo VS, Rojas VCT, de Oliveira MK, Vilela FC, Giusti-Paiva A, Barbosa G, Lima LM, Pinheiro GB, Veras LG, Mortari MR, Tarozzi A, Viegas C Jr. Cristancho Ortiz CJ, et al. Among authors: dardenne le. RSC Med Chem. 2022 Mar 17;13(5):568-584. doi: 10.1039/d1md00374g. eCollection 2022 May 25. RSC Med Chem. 2022. PMID: 35694691 Free PMC article.
Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease.
de Freitas Silva M, Tardelli Lima E, Pruccoli L, Castro NG, Guimarães MJR, M R da Silva F, Fonseca Nadur N, de Azevedo LL, Kümmerle AE, Guedes IA, Dardenne LE, Gontijo VS, Tarozzi A, Viegas C. de Freitas Silva M, et al. Among authors: dardenne le. Molecules. 2020 Jul 10;25(14):3165. doi: 10.3390/molecules25143165. Molecules. 2020. PMID: 32664425 Free PMC article.
Anti-Restriction Gene Homologs Are Highly Represented in Methicillin-Resistant and Multidrug-Resistant Staphylococcus aureus ST239 and ST398: Implications for Resistance Gene Acquisitions.
Silva DNS, Beltrame CO, Botelho AMN, Martini CL, Esteves MAC, Guedes IA, Dardenne LE, Figueiredo AMS. Silva DNS, et al. Among authors: dardenne le. Antibiotics (Basel). 2022 Sep 8;11(9):1217. doi: 10.3390/antibiotics11091217. Antibiotics (Basel). 2022. PMID: 36139996 Free PMC article.
Novel series of tacrine-tianeptine hybrids: Synthesis, cholinesterase inhibitory activity, S100B secretion and a molecular modeling approach.
Ceschi MA, da Costa JS, Lopes JPB, Câmara VS, Campo LF, Borges ACA, Gonçalves CAS, de Souza DF, Konrath EL, Karl ALM, Guedes IA, Dardenne LE. Ceschi MA, et al. Among authors: dardenne le. Eur J Med Chem. 2016 Oct 4;121:758-772. doi: 10.1016/j.ejmech.2016.06.025. Epub 2016 Jun 23. Eur J Med Chem. 2016. PMID: 27392529
Design, synthesis, cholinesterase inhibition and molecular modelling study of novel tacrine hybrids with carbohydrate derivatives.
Lopes JPB, Silva L, da Costa Franarin G, Antonio Ceschi M, Seibert Lüdtke D, Ferreira Dantas R, de Salles CMC, Paes Silva-Jr F, Roberto Senger M, Alvim Guedes I, Emmanuel Dardenne L. Lopes JPB, et al. Among authors: emmanuel dardenne l. Bioorg Med Chem. 2018 Nov 1;26(20):5566-5577. doi: 10.1016/j.bmc.2018.10.003. Epub 2018 Oct 9. Bioorg Med Chem. 2018. PMID: 30340901
13 results