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A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice.
Calls A, Torres-Espin A, Tormo M, Martínez-Escardó L, Bonet N, Casals F, Navarro X, Yuste VJ, Udina E, Bruna J. Calls A, et al. Among authors: martinez escardo l. Ann Clin Transl Neurol. 2022 Dec;9(12):1985-1998. doi: 10.1002/acn3.51691. Epub 2022 Nov 11. Ann Clin Transl Neurol. 2022. PMID: 36369764 Free PMC article.
Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics.
Koessinger AL, Cloix C, Koessinger D, Heiland DH, Bock FJ, Strathdee K, Kinch K, Martínez-Escardó L, Paul NR, Nixon C, Malviya G, Jackson MR, Campbell KJ, Stevenson K, Davis S, Elmasry Y, Ahmed A, O'Prey J, Ichim G, Schnell O, Stewart W, Blyth K, Ryan KM, Chalmers AJ, Norman JC, Tait SWG. Koessinger AL, et al. Among authors: martinez escardo l. Cell Death Differ. 2022 Oct;29(10):2089-2104. doi: 10.1038/s41418-022-01001-3. Epub 2022 Apr 26. Cell Death Differ. 2022. PMID: 35473984 Free PMC article.
Gossypol Treatment Restores Insufficient Apoptotic Function of DFF40/CAD in Human Glioblastoma Cells.
Martínez-Escardó L, Alemany M, Sánchez-Osuna M, Sánchez-Chardi A, Roig-Martínez M, Suárez-García S, Ruiz-Molina D, Vidal N, Plans G, Majós C, Ribas J, Baltrons MA, Bayascas JR, Barcia C, Bruna J, Yuste VJ. Martínez-Escardó L, et al. Cancers (Basel). 2021 Nov 8;13(21):5579. doi: 10.3390/cancers13215579. Cancers (Basel). 2021. PMID: 34771741 Free PMC article.
An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.
Garcia-Belinchón M, Sánchez-Osuna M, Martínez-Escardó L, Granados-Colomina C, Pascual-Guiral S, Iglesias-Guimarais V, Casanelles E, Ribas J, Yuste VJ. Garcia-Belinchón M, et al. Among authors: martinez escardo l. J Biol Chem. 2015 Aug 21;290(34):20841-20855. doi: 10.1074/jbc.M115.644179. Epub 2015 Jun 29. J Biol Chem. 2015. PMID: 26124276 Free PMC article.
An intrinsic DFF40/CAD endonuclease deficiency impairs oligonucleosomal DNA hydrolysis during caspase-dependent cell death: a common trait in human glioblastoma cells.
Sánchez-Osuna M, Martínez-Escardó L, Granados-Colomina C, Martínez-Soler F, Pascual-Guiral S, Iglesias-Guimarais V, Velasco R, Plans G, Vidal N, Tortosa A, Barcia C, Bruna J, Yuste VJ. Sánchez-Osuna M, et al. Among authors: martinez escardo l. Neuro Oncol. 2016 Jul;18(7):950-61. doi: 10.1093/neuonc/nov315. Epub 2016 Jan 10. Neuro Oncol. 2016. PMID: 26755073 Free PMC article.