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Year Number of Results
2010 2
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2012 1
2014 2
2015 3
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2018 2
2019 3
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2023 1
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15 results

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Page 1
Tuning Hsp104 specificity to selectively detoxify α-synuclein.
Mack KL, Kim H, Barbieri EM, Lin J, Braganza S, Jackrel ME, DeNizio JE, Yan X, Chuang E, Tariq A, Cupo RR, Castellano LM, Caldwell KA, Caldwell GA, Shorter J. Mack KL, et al. Among authors: castellano lm. Mol Cell. 2023 Sep 21;83(18):3314-3332.e9. doi: 10.1016/j.molcel.2023.07.029. Epub 2023 Aug 24. Mol Cell. 2023. PMID: 37625404
Therapeutic genetic variation revealed in diverse Hsp104 homologs.
March ZM, Sweeney K, Kim H, Yan X, Castellano LM, Jackrel ME, Lin J, Chuang E, Gomes E, Willicott CW, Michalska K, Jedrzejczak RP, Joachimiak A, Caldwell KA, Caldwell GA, Shalem O, Shorter J. March ZM, et al. Among authors: castellano lm. Elife. 2020 Dec 15;9:e57457. doi: 10.7554/eLife.57457. Elife. 2020. PMID: 33319748 Free PMC article.
Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events.
Michalska K, Zhang K, March ZM, Hatzos-Skintges C, Pintilie G, Bigelow L, Castellano LM, Miles LJ, Jackrel ME, Chuang E, Jedrzejczak R, Shorter J, Chiu W, Joachimiak A. Michalska K, et al. Among authors: castellano lm. Structure. 2019 Mar 5;27(3):449-463.e7. doi: 10.1016/j.str.2018.11.001. Epub 2018 Dec 27. Structure. 2019. PMID: 30595457 Free PMC article.
Suramin inhibits Hsp104 ATPase and disaggregase activity.
Torrente MP, Castellano LM, Shorter J. Torrente MP, et al. Among authors: castellano lm. PLoS One. 2014 Oct 9;9(10):e110115. doi: 10.1371/journal.pone.0110115. eCollection 2014. PLoS One. 2014. PMID: 25299406 Free PMC article.
A molecular tweezer antagonizes seminal amyloids and HIV infection.
Lump E, Castellano LM, Meier C, Seeliger J, Erwin N, Sperlich B, Stürzel CM, Usmani S, Hammond RM, von Einem J, Gerold G, Kreppel F, Bravo-Rodriguez K, Pietschmann T, Holmes VM, Palesch D, Zirafi O, Weissman D, Sowislok A, Wettig B, Heid C, Kirchhoff F, Weil T, Klärner FG, Schrader T, Bitan G, Sanchez-Garcia E, Winter R, Shorter J, Münch J. Lump E, et al. Among authors: castellano lm. Elife. 2015 Aug 18;4:e05397. doi: 10.7554/eLife.05397. Elife. 2015. PMID: 26284498 Free PMC article.
15 results