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Role of plasminogen activator inhibitor-1 in oral tongue squamous cell carcinoma: An immunohistochemical and in vitro analysis.
Mafra RP, Sabino VG, Rolim LSA, de Carvalho CHP, Nonaka CFW, Barboza CAG, de Souza LB, Pinto LP. Mafra RP, et al. Exp Mol Pathol. 2022 Feb;124:104722. doi: 10.1016/j.yexmp.2021.104722. Epub 2021 Nov 17. Exp Mol Pathol. 2022. PMID: 34800515
Cell viability (p = 0.020) and progression to the S-phase of the cell cycle (p = 0.024) were higher in G10 and G20 at 24 h. The percentages of apoptotic/necrotic cells were not affected by rhPAI-1. The presence of rhPAI-1 increased cell migration (p = 0.039) …
Cell viability (p = 0.020) and progression to the S-phase of the cell cycle (p = 0.024) were higher in G10 and G20 at 24 h. Th …
Immunocastration of goats using anti-gonadotrophin releasing hormone vaccine.
Lents MP, Barbosa LP, Santana ALA, Pinheiro EEG, Mugabe LC, Biscarde CEA, Kiya CK, Machado WM, Souza RS. Lents MP, et al. Theriogenology. 2018 Jul 1;114:7-13. doi: 10.1016/j.theriogenology.2018.03.013. Epub 2018 Mar 15. Theriogenology. 2018. PMID: 29574307 Clinical Trial.

A reduction in width and length of the right and left testicles was observed and, consequently, the scrotal circumference of the immunized animals reduced after the second vaccine application (P < 0.05). Thirty-days after the first vaccine application, there was a negat

A reduction in width and length of the right and left testicles was observed and, consequently, the scrotal circumference of the immunized a …
Effects of climate variability on respiratory diseases in the Western Region of Bahia, Brazil.
Quesado EML, Souza TMO, Venancio LPR. Quesado EML, et al. Public Health. 2023 Sep;222:1-6. doi: 10.1016/j.puhe.2023.06.030. Epub 2023 Jul 21. Public Health. 2023. PMID: 37481802
A significant negative correlation was observed between respiratory diseases and rainfall (r = -0.70, P = 0.011). CONCLUSIONS: Pneumonia and asthma remain important causes of hospitalisation among children in the Western Bahia Region. ...
A significant negative correlation was observed between respiratory diseases and rainfall (r = -0.70, P = 0.011). CONCLUSIONS: Pneumo …
Risk for postpartum depressive symptoms among pregnant women in a tertiary care setting with and without a positive COVID-19 test.
Taljan KE, Cantu-Weinstein A, McKenna M, De Souza L, Meng Y, Gonsalves L, Goje O, Viguera AC. Taljan KE, et al. Gen Hosp Psychiatry. 2022 Nov-Dec;79:1-6. doi: 10.1016/j.genhosppsych.2022.08.006. Epub 2022 Sep 6. Gen Hosp Psychiatry. 2022. PMID: 36108453 Free PMC article.
We found no significant differences in rates of positive responses to screening questions (14/129, 10.9% vs. 72/516, 14.0%; p = .35) or EPDS scores >9 (6/97, 6.2% vs. 42/410, 10.2%; p = .22). Prior history of psychiatric illness was the only significant predictor …
We found no significant differences in rates of positive responses to screening questions (14/129, 10.9% vs. 72/516, 14.0%; p = .35) …
Cannabis sativa L. roots from Northeast Brazil reduce abdominal contortions in a mouse model of primary dysmenorrhea.
Araújo TCL, Menezes PMN, Ribeiro TF, Macêdo CAF, Souza NAC, Lima KSB, Figueredo HF, Silva FS, Rolim LA. Araújo TCL, et al. J Ethnopharmacol. 2024 Jan 10;318(Pt A):116891. doi: 10.1016/j.jep.2023.116891. Epub 2023 Jul 8. J Ethnopharmacol. 2024. PMID: 37423518
RESULTS: The data obtained by HPLC-MS suggested the presence of four substances: cannabisativine, anhydrocannabisativine, feruloyltyramine, and p-coumaroyltyramine. In the pharmacological assays, the AqECsR showed no spasmolytic effect. ...
RESULTS: The data obtained by HPLC-MS suggested the presence of four substances: cannabisativine, anhydrocannabisativine, feruloyltyramine, …
Comparison of the New Oral Anticoagulants and Warfarin in Patients with Atrial Fibrillation and Valvular Heart Disease: Systematic Review and Meta-Analysis.
de Souza Lima Bitar Y, Neto MG, Filho JAL, Pereira LV, Travassos KSO, Akrami KM, Roever L, Duraes AR. de Souza Lima Bitar Y, et al. Drugs R D. 2019 Jun;19(2):117-126. doi: 10.1007/s40268-019-0274-z. Drugs R D. 2019. PMID: 31055767 Free PMC article.
NOACs significantly reduced the risk of stroke/SE (RR 0.78; 95% CI 0.66-0.91; P = 0.002) and intracranial hemorrhage (RR 0.51; 95% CI 0.33-0.79; P = 0.003) and lowered the risk of major bleeding (RR 0.77; 95% CI 0.58-1.02; P = 0.07) compared with warfarin. .. …
NOACs significantly reduced the risk of stroke/SE (RR 0.78; 95% CI 0.66-0.91; P = 0.002) and intracranial hemorrhage (RR 0.51; 95% CI …
Choices of Stent and Cerebral Protection in the Ongoing ACST-2 Trial: A Descriptive Study.
de Waard DD, Halliday A, de Borst GJ, Bulbulia R, Huibers A, Casana R, Bonati LH, Tolva V; ACST-2 Collaborative Group. de Waard DD, et al. Eur J Vasc Endovasc Surg. 2017 May;53(5):617-625. doi: 10.1016/j.ejvs.2016.12.034. Epub 2017 Mar 11. Eur J Vasc Endovasc Surg. 2017. PMID: 28291675 Free article. Clinical Trial.
Vascular surgeons used a CPD significantly more often than interventional radiologists (98.6% vs. 76.3%; p < .001), but this choice did not appear to be dependent on patient characteristics. ...

Vascular surgeons used a CPD significantly more often than interventional radiologists (98.6% vs. 76.3%; p < .001), but this choic