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2015 1
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2020 2
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Page 1
Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity.
Iqbal F, Schlotter F, Becker-Greene D, Lupieri A, Goettsch C, Hutcheson JD, Rogers MA, Itoh S, Halu A, Lee LH, Blaser MC, Mlynarchik AK, Hagita S, Kuraoka S, Chen HY, Engert JC, Passos LSA, Jha PK, Osborn EA, Jaffer FA, Body SC, Robson SC, Thanassoulis G, Aikawa M, Singh SA, Sonawane AR, Aikawa E. Iqbal F, et al. Eur Heart J. 2023 Mar 7;44(10):885-898. doi: 10.1093/eurheartj/ehac818. Eur Heart J. 2023. PMID: 36660854 Free PMC article.
Preclinical Characterization and Phase I Study of an Anti-HER2-TLR7 Immune-Stimulator Antibody Conjugate in Patients with HER2+ Malignancies.
Janku F, Han SW, Doi T, Amatu A, Ajani JA, Kuboki Y, Cortez A, Cellitti SE, Mahling PC, Subramanian K, Schoenfeld HA, Choi SM, Iaconis LA, Lee LH, Pelletier MR, Dranoff G, Askoxylakis V, Siena S. Janku F, et al. Cancer Immunol Res. 2022 Dec 2;10(12):1441-1461. doi: 10.1158/2326-6066.CIR-21-0722. Cancer Immunol Res. 2022. PMID: 36129967 Clinical Trial.
Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling.
Nakano T, Katsuki S, Chen M, Decano JL, Halu A, Lee LH, Pestana DVS, Kum AST, Kuromoto RK, Golden WS, Boff MS, Guimaraes GC, Higashi H, Kauffman KJ, Maejima T, Suzuki T, Iwata H, Barabási AL, Aster JC, Anderson DG, Sharma A, Singh SA, Aikawa E, Aikawa M. Nakano T, et al. Circulation. 2019 Jan 2;139(1):78-96. doi: 10.1161/CIRCULATIONAHA.118.034588. Circulation. 2019. PMID: 30586693 Free PMC article.
Second Heart Field-Derived Cells Contribute to Angiotensin II-Mediated Ascending Aortopathies.
Sawada H, Katsumata Y, Higashi H, Zhang C, Li Y, Morgan S, Lee LH, Singh SA, Chen JZ, Franklin MK, Moorleghen JJ, Howatt DA, Rateri DL, Shen YH, LeMaire SA, Aikawa M, Majesky MW, Lu HS, Daugherty A. Sawada H, et al. Among authors: lee lh. Circulation. 2022 Mar 29;145(13):987-1001. doi: 10.1161/CIRCULATIONAHA.121.058173. Epub 2022 Feb 10. Circulation. 2022. PMID: 35143327 Free PMC article.
A disease-driver population within interstitial cells of human calcific aortic valves identified via single-cell and proteomic profiling.
Decano JL, Iwamoto Y, Goto S, Lee JY, Matamalas JT, Halu A, Blaser M, Lee LH, Pieper B, Chelvanambi S, Silva-Nicolau J, Bartoli-Leonard F, Higashi H, Shibata H, Vyas P, Wang J, Gostjeva E, Body SC, Singh SA, Aikawa M, Aikawa E. Decano JL, et al. Cell Rep. 2022 Apr 12;39(2):110685. doi: 10.1016/j.celrep.2022.110685. Cell Rep. 2022. PMID: 35417712 Free article.
Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis.
Rogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K, Daaboul G, Bouten CVC, Body SC, Singh SA, Bertazzo S, Libby P, Aikawa M, Aikawa E. Rogers MA, et al. Among authors: lee lh. Sci Adv. 2020 Sep 16;6(38):eabb1244. doi: 10.1126/sciadv.abb1244. Print 2020 Sep. Sci Adv. 2020. PMID: 32938681 Free PMC article.
20 results