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The olfactory co-receptor Orco from the migratory locust (Locusta migratoria) and the desert locust (Schistocerca gregaria): identification and expression pattern.
Yang Y, Krieger J, Zhang L, Breer H. Yang Y, et al. Int J Biol Sci. 2012;8(2):159-70. doi: 10.7150/ijbs.8.159. Epub 2011 Dec 13. Int J Biol Sci. 2012. PMID: 22211114 Free PMC article.
The Orco-expressing cells in the antenna of S. gregaria and L. migratoria were visualized by in situ hybridization. ...No Orco-positive cells were detected in sensilla coeloconica and sensilla chaetica. ...
The Orco-expressing cells in the antenna of S. gregaria and L. migratoria were visualized by in situ hybridization. ...No O
Molecular characterization and immunolocalization of the olfactory co-receptor Orco from two blood-feeding muscid flies, the stable fly (Stomoxys calcitrans, L.) and the horn fly (Haematobia irritans irritans, L.).
Olafson PU. Olafson PU. Insect Mol Biol. 2013 Apr;22(2):131-42. doi: 10.1111/imb.12009. Epub 2013 Jan 1. Insect Mol Biol. 2013. PMID: 23278866 Free PMC article.
In an effort to expand our understanding of biting fly chemosensory pathways, transcripts encoding the highly conserved insect odorant co-receptor (Orco) were isolated from two representative biting fly species, the stable fly (Scal\Orco) and the horn fly (Hirr\O
In an effort to expand our understanding of biting fly chemosensory pathways, transcripts encoding the highly conserved insect odorant co-re …
Mutagenesis of the orco odorant receptor co-receptor impairs olfactory function in the malaria vector Anopheles coluzzii.
Sun H, Liu F, Ye Z, Baker A, Zwiebel LJ. Sun H, et al. Insect Biochem Mol Biol. 2020 Dec;127:103497. doi: 10.1016/j.ibmb.2020.103497. Epub 2020 Nov 11. Insect Biochem Mol Biol. 2020. PMID: 33188923 Free PMC article.
To examine the mechanistic and functional contributions of Orco/OR complexes to the chemosensory processes of An. coluzzii, we utilized CRISPR/Cas9 gene editing to create a line of homozygous, Orco-knockout, mutant mosquitoes. As expected, orco(-/-) ORNs acro …
To examine the mechanistic and functional contributions of Orco/OR complexes to the chemosensory processes of An. coluzzii, we utiliz …
The odorant receptor co-receptor from the bed bug, Cimex lectularius L.
Hansen IA, Rodriguez SD, Drake LL, Price DP, Blakely BN, Hammond JI, Tsujimoto H, Monroy EY, Maio WA, Romero A. Hansen IA, et al. PLoS One. 2014 Nov 20;9(11):e113692. doi: 10.1371/journal.pone.0113692. eCollection 2014. PLoS One. 2014. PMID: 25411789 Free PMC article.
In this study, we have performed RNAseq of bed bug sensory organs and identified several odorant receptors as well as Orco. We characterized Orco expression and investigated the effect of chemicals targeting Orco on bed bug behavior and reproduction. We have …
In this study, we have performed RNAseq of bed bug sensory organs and identified several odorant receptors as well as Orco. We charac …
The odorant receptor co-receptor gene contributes to mating and host-searching behaviors in parasitoid wasps.
Zhang Q, Chen J, Wang Y, Lu Y, Dong Z, Shi W, Pang L, Ren S, Chen X, Huang J. Zhang Q, et al. Pest Manag Sci. 2023 Jan;79(1):454-463. doi: 10.1002/ps.7214. Epub 2022 Oct 13. Pest Manag Sci. 2023. PMID: 36177949
RESULTS: We identified the full-length Orco genes of four Drosophila parasitoid species in the genus Leptopilina, namely L. heterotoma, L. boulardi, L. syphax and L. drosophilae. ...After knockdown of Orco in these different parasitoid sp …
RESULTS: We identified the full-length Orco genes of four Drosophila parasitoid species in the genus Leptopilina, namely L. he …
Profile, Healthcare Resource Consumption and Related Costs in ANCA-Associated Vasculitis Patients: A Real-World Analysis in Italy.
Degli Esposti L, Dovizio M, Perrone V, Veronesi C, Andretta M, Bacca M, Barbieri A, Bartolini F, Cavaliere A, Chinellato A, Ciaccia A, Cillo M, Citraro R, Costantini A, Dell'Orco S, Ferrante F, Gentile S, Grego S, Mancini D, Moscogiuri R, Mosele E, Pagliaro R, Procacci C, Re D, Santoleri F, Ubertazzo L, Vercellone A, Ramirez de Arellano A, Gigliotti G, Quartuccio L. Degli Esposti L, et al. Adv Ther. 2023 Dec;40(12):5338-5353. doi: 10.1007/s12325-023-02681-0. Epub 2023 Oct 3. Adv Ther. 2023. PMID: 37787877 Free PMC article.
Characterization and Comparative Analysis of Olfactory Receptor Co-Receptor Orco Orthologs Among Five Mirid Bug Species.
Wang Q, Wang Q, Zhou YL, Shan S, Cui HH, Xiao Y, Dong K, Khashaveh A, Sun L, Zhang YJ. Wang Q, et al. Front Physiol. 2018 Mar 5;9:158. doi: 10.3389/fphys.2018.00158. eCollection 2018. Front Physiol. 2018. PMID: 29556202 Free PMC article.
In the odorant detection pathway, olfactory receptor co-receptor (Orco) plays critical role in the perception of odors. In this study, we identified the full-length cDNA sequences encoding three putative Orcos (AsutOrco, AfasOrco, and LpraOrco) in bug species of A. sutural …
In the odorant detection pathway, olfactory receptor co-receptor (Orco) plays critical role in the perception of odors. In this study …
Bioactivities and modes of action of VUAA1.
Yang L, Demares F, Norris EJ, Jiang S, Bernier UR, Bloomquist JR. Yang L, et al. Pest Manag Sci. 2021 Aug;77(8):3685-3692. doi: 10.1002/ps.6023. Epub 2020 Aug 25. Pest Manag Sci. 2021. PMID: 32741076
BACKGROUND: The compound 2-((4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-ethylphenyl) acetamide (VUAA1) is reported to be an odorant receptor co-receptor (Orco) agonist in insects with potential use as an insect repellent. ...VUAA1 showed a two-phase effect o …
BACKGROUND: The compound 2-((4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-ethylphenyl) acetamide (VUAA1) is reported to be an o …
TRPA1 modulates noxious odor responses in Lygus hesperus.
Hull JJ, Yang YW, Miyasaki K, Brent CS. Hull JJ, et al. J Insect Physiol. 2020 Apr;122:104038. doi: 10.1016/j.jinsphys.2020.104038. Epub 2020 Feb 27. J Insect Physiol. 2020. PMID: 32113955
Towards this end, we investigated allyl isothiocyanate, cinnamaldehyde and citronellal, compounds that are noxious repellents to other insects. We found that L. hesperus avoided areas containing the three compounds and that exposure induced increases in movement velocity a …
Towards this end, we investigated allyl isothiocyanate, cinnamaldehyde and citronellal, compounds that are noxious repellents to other insec …
Identification of the western tarnished plant bug (Lygus hesperus) olfactory co-receptor Orco: expression profile and confirmation of atypical membrane topology.
Hull JJ, Hoffmann EJ, Perera OP, Snodgrass GL. Hull JJ, et al. Arch Insect Biochem Physiol. 2012 Dec;81(4):179-98. doi: 10.1002/arch.21042. Epub 2012 Jul 26. Arch Insect Biochem Physiol. 2012. PMID: 22836832
To begin to address this issue, we utilized homology-based PCR as a commonly accepted abbreviation but if necessary it is polymerase chain reaction methods to identify the L. hesperus olfactory receptor co-receptor (Orco) ortholog, a receptor that has been shown to …
To begin to address this issue, we utilized homology-based PCR as a commonly accepted abbreviation but if necessary it is polymerase chain r …
25 results