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Page 1
Enhancer-driven transcriptional regulation is a potential key determinant for human visceral and subcutaneous adipocytes.
Biochim Biophys Acta Gene Regul Mech. 2018 Jun 30:S1874-9399(18)30095-6. doi: 10.1016/j.bbagrm.2018.06.007. Online ahead of print.
Biochim Biophys Acta Gene Regul Mech. 2018.
PMID: 29966764
Impact of Promoter Polymorphisms on the Transcriptional Regulation of the Organic Cation Transporter OCT1 (SLC22A1).
Bokelmann K, Brockmöller J, Tzvetkov MV.
Bokelmann K, et al.
J Pers Med. 2018 Dec 11;8(4):42. doi: 10.3390/jpm8040042.
J Pers Med. 2018.
PMID: 30544975
Free PMC article.
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A novel missense variant in the SDR domain of the WWOX gene leads to complete loss of WWOX protein with early-onset epileptic encephalopathy and severe developmental delay.
Johannsen J, Kortüm F, Rosenberger G, Bokelmann K, Schirmer MA, Denecke J, Santer R.
Johannsen J, et al. Among authors: bokelmann k.
Neurogenetics. 2018 Aug;19(3):151-156. doi: 10.1007/s10048-018-0549-5. Epub 2018 May 28.
Neurogenetics. 2018.
PMID: 29808465
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Hepatocyte nuclear factor 1 regulates the expression of the organic cation transporter 1 via binding to an evolutionary conserved region in intron 1 of the OCT1 gene.
O'Brien VP, Bokelmann K, Ramírez J, Jobst K, Ratain MJ, Brockmöller J, Tzvetkov MV.
O'Brien VP, et al. Among authors: bokelmann k.
J Pharmacol Exp Ther. 2013 Oct;347(1):181-92. doi: 10.1124/jpet.113.206359. Epub 2013 Aug 6.
J Pharmacol Exp Ther. 2013.
PMID: 23922447
Free PMC article.
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Functional characterization of a -100_-102delAAG deletion-insertion polymorphism in the promoter region of the HTR3B gene.
Meineke C, Tzvetkov MV, Bokelmann K, Oetjen E, Hirsch-Ernst K, Kaiser R, Brockmöller J.
Meineke C, et al. Among authors: bokelmann k.
Pharmacogenet Genomics. 2008 Mar;18(3):219-30. doi: 10.1097/FPC.0b013e3282f51092.
Pharmacogenet Genomics. 2008.
PMID: 18300944
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Does the haplotype Met408-Del420, which was apparently predictive for imatinib efficacy, really exist and how strongly may it affect OCT1 activity?
Tzvetkov MV, Seitz T, Bokelmann K, Mueller T, Brockmöller J, Koepsell H.
Tzvetkov MV, et al. Among authors: bokelmann k.
Blood. 2014 Feb 27;123(9):1427-9. doi: 10.1182/blood-2013-11-535864.
Blood. 2014.
PMID: 24578499
Free article.
No abstract available.
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