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Page 1
Synthesis and biophysical properties of 5'-thio-2',4'-BNA/LNA oligonucleotide.
Bioorg Med Chem. 2018 Jul 23;26(12):3634-3638. doi: 10.1016/j.bmc.2018.05.040. Epub 2018 May 23.
Bioorg Med Chem. 2018.
PMID: 29886084
Drug discovery and development scheme for liver-targeting bridged nucleic acid antisense oligonucleotides.
Wada F, Yamamoto T, Kobayashi T, Tachibana K, Ito KR, Hamasaki M, Kayaba Y, Terada C, Yamayoshi A, Obika S, Harada-Shiba M.
Wada F, et al. Among authors: ito kr.
Mol Ther Nucleic Acids. 2021 Oct 19;26:957-969. doi: 10.1016/j.omtn.2021.10.008. eCollection 2021 Dec 3.
Mol Ther Nucleic Acids. 2021.
PMID: 34760338
Free PMC article.
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Hybridization and Mismatch Discrimination Abilities of 2',4'-Bridged Nucleic Acids Bearing 2-Thiothymine or 2-Selenothymine Nucleobase.
Habuchi T, Yamaguchi T, Aoyama H, Horiba M, Ito KR, Obika S.
Habuchi T, et al. Among authors: ito kr.
J Org Chem. 2019 Feb 1;84(3):1430-1439. doi: 10.1021/acs.joc.8b02863. Epub 2019 Jan 24.
J Org Chem. 2019.
PMID: 30632750
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Synthesis and Properties of 7-Deazapurine- and 8-Aza-7-deazapurine-Locked Nucleic Acid Analogues: Effect of the Glycosidic Torsion Angle.
Hara T, Kodama T, Takegaki Y, Morihiro K, Ito KR, Obika S.
Hara T, et al. Among authors: ito kr.
J Org Chem. 2017 Jan 6;82(1):25-36. doi: 10.1021/acs.joc.6b02525. Epub 2016 Dec 15.
J Org Chem. 2017.
PMID: 27958739
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In vitro and in vivo biophysical properties of oligonucleotides containing 5'-thio nucleosides.
Islam MA, Waki R, Fujisaka A, Ito KR, Obika S.
Islam MA, et al. Among authors: ito kr.
Drug Discov Ther. 2016;10(5):263-270. doi: 10.5582/ddt.2016.01055.
Drug Discov Ther. 2016.
PMID: 27890900
Free article.
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Double-stranded DNA-templated cleavage of oligonucleotides containing a P3'->N5' linkage triggered by triplex formation: the effects of chemical modifications and remarkable enhancement in reactivity.
Ito KR, Kodama T, Tomizu M, Negoro Y, Orita A, Osaki T, Hosoki N, Tanaka T, Imanishi T, Obika S.
Ito KR, et al.
Nucleic Acids Res. 2010 Nov;38(20):7332-42. doi: 10.1093/nar/gkq600. Epub 2010 Jul 8.
Nucleic Acids Res. 2010.
PMID: 20615902
Free PMC article.
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Cleavage of oligonucleotides containing a P3'→N5' phosphoramidate linkage mediated by single-stranded oligonucleotide templates.
Ito KR, Kodama T, Makimura F, Hosoki N, Osaki T, Orita A, Imanishi T, Obika S.
Ito KR, et al.
Molecules. 2011 Dec 20;16(12):10695-708. doi: 10.3390/molecules161210695.
Molecules. 2011.
PMID: 22186956
Free PMC article.
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