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Phase I/II trial of a peptide-based COVID-19 T-cell activator in patients with B-cell deficiency.
Heitmann JS, Tandler C, Marconato M, Nelde A, Habibzada T, Rittig SM, Tegeler CM, Maringer Y, Jaeger SU, Denk M, Richter M, Oezbek MT, Wiesmüller KH, Bauer J, Rieth J, Wacker M, Schroeder SM, Hoenisch Gravel N, Scheid J, Märklin M, Henrich A, Klimovich B, Clar KL, Lutz M, Holzmayer S, Hörber S, Peter A, Meisner C, Fischer I, Löffler MW, Peuker CA, Habringer S, Goetze TO, Jäger E, Rammensee HG, Salih HR, Walz JS. Heitmann JS, et al. Among authors: clar kl. Nat Commun. 2023 Aug 18;14(1):5032. doi: 10.1038/s41467-023-40758-0. Nat Commun. 2023. PMID: 37596280 Free PMC article. Clinical Trial.
Platelet-expressed immune checkpoint regulator GITRL in breast cancer.
Zhou Y, Heitmann JS, Clar KL, Kropp KN, Hinterleitner M, Engler T, Koch A, Hartkopf AD, Zender L, Salih HR, Maurer S, Hinterleitner C. Zhou Y, et al. Among authors: clar kl. Cancer Immunol Immunother. 2021 Sep;70(9):2483-2496. doi: 10.1007/s00262-021-02866-y. Epub 2021 Feb 4. Cancer Immunol Immunother. 2021. PMID: 33538861 Free PMC article.
The novel deubiquitinase inhibitor b-AP15 induces direct and NK cell-mediated antitumor effects in human mantle cell lymphoma.
Kropp KN, Maurer S, Rothfelder K, Schmied BJ, Clar KL, Schmidt M, Strunz B, Kopp HG, Steinle A, Grünebach F, Rittig SM, Salih HR, Dörfel D. Kropp KN, et al. Among authors: clar kl. Cancer Immunol Immunother. 2018 Jun;67(6):935-947. doi: 10.1007/s00262-018-2151-y. Epub 2018 Mar 19. Cancer Immunol Immunother. 2018. PMID: 29556699