Introduction: Perivalvular abscess in native valve infective endocarditis (IE) is associated with significantly increased mortality.
Case description: Herein, we report a 29 year old Indian male who presented with culture negative IE with perivalvular abscess and severe mitral regurgitation requiring mitral valve replacement.
Discussion: Initial approach is very difficult in terms of when IE presents as culture negative. This case highlights the important role of echocardiography in the management of culture negative IE.
Keywords: Blood culture negative infective endocarditis; Case report; Mitral valve abscess; Mitral valve replacement.