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TRPA1 is essential for the vascular response to environmental cold exposure.
Aubdool AA, Graepel R, Kodji X, Alawi KM, Bodkin JV, Srivastava S, Gentry C, Heads R, Grant AD, Fernandes ES, Bevan S, Brain SD. Aubdool AA, et al. Among authors: alawi km. Nat Commun. 2014 Dec 11;5:5732. doi: 10.1038/ncomms6732. Nat Commun. 2014. PMID: 25501034 Free PMC article.
A Novel α-Calcitonin Gene-Related Peptide Analogue Protects Against End-Organ Damage in Experimental Hypertension, Cardiac Hypertrophy, and Heart Failure.
Aubdool AA, Thakore P, Argunhan F, Smillie SJ, Schnelle M, Srivastava S, Alawi KM, Wilde E, Mitchell J, Farrell-Dillon K, Richards DA, Maltese G, Siow RC, Nandi M, Clark JE, Shah AM, Sams A, Brain SD. Aubdool AA, et al. Among authors: alawi km. Circulation. 2017 Jul 25;136(4):367-383. doi: 10.1161/CIRCULATIONAHA.117.028388. Epub 2017 Apr 26. Circulation. 2017. PMID: 28446517 Free PMC article.
Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner.
Fernandes ES, Russell FA, Alawi KM, Sand C, Liang L, Salamon R, Bodkin JV, Aubdool AA, Arno M, Gentry C, Smillie SJ, Bevan S, Keeble JE, Malcangio M, Brain SD. Fernandes ES, et al. Among authors: alawi km. Arthritis Res Ther. 2016 Jan 11;18:7. doi: 10.1186/s13075-015-0905-x. Arthritis Res Ther. 2016. PMID: 26754745 Free PMC article.