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ATF2 loss promotes tumor invasion in colorectal cancer cells via upregulation of cancer driver TROP2.
Huebner K, Erlenbach-Wuensch K, Prochazka J, Sheraj I, Hampel C, Mrazkova B, Michalcikova T, Tureckova J, Iatsiuk V, Weissmann A, Ferrazzi F, Kunze P, Nalli E, Sammer E, Gehring A, Cheema MM, Eckstein M, Paap EM, Soederberg A, Fischer C, Paul S, Mahadevan V, Ndreshkjana B, Meier MA, Muehlich S, Geppert CI, Merkel S, Grutzmann R, Roehe A, Banerjee S, Hartmann A, Sedlacek R, Schneider-Stock R. Huebner K, et al. Cell Mol Life Sci. 2022 Jul 15;79(8):423. doi: 10.1007/s00018-022-04445-5. Cell Mol Life Sci. 2022. PMID: 35838828 Free PMC article.
A partial epithelial-mesenchymal transition signature for highly aggressive colorectal cancer cells that survive under nutrient restriction.
Pastorino GA, Sheraj I, Huebner K, Ferrero G, Kunze P, Hartmann A, Hampel C, Husnugil HH, Maiuthed A, Gebhart F, Schlattmann F, Gulec Taskiran AE, Oral G, Palmisano R, Pardini B, Naccarati A, Erlenbach-Wuensch K, Banerjee S, Schneider-Stock R. Pastorino GA, et al. Among authors: huebner k. J Pathol. 2024 Mar;262(3):347-361. doi: 10.1002/path.6240. Epub 2024 Jan 18. J Pathol. 2024. PMID: 38235615
Combination of 5-fluorouracil and thymoquinone targets stem cell gene signature in colorectal cancer cells.
Ndreshkjana B, Çapci A, Klein V, Chanvorachote P, Muenzner JK, Huebner K, Steinmann S, Erlenbach-Wuensch K, Geppert CI, Agaimy A, Ballout F, El-Baba C, Gali-Muhtasib H, Roehe AV, Hartmann A, Tsogoeva SB, Schneider-Stock R. Ndreshkjana B, et al. Among authors: huebner k. Cell Death Dis. 2019 May 16;10(6):379. doi: 10.1038/s41419-019-1611-4. Cell Death Dis. 2019. PMID: 31097715 Free PMC article.
A Gene Signature Derived from the Loss of CDKN1A (p21) Is Associated with CMS4 Colorectal Cancer.
Bueno-Fortes S, Muenzner JK, Berral-Gonzalez A, Hampel C, Lindner P, Berninger A, Huebner K, Kunze P, Bäuerle T, Erlenbach-Wuensch K, Sánchez-Santos JM, Hartmann A, De Las Rivas J, Schneider-Stock R. Bueno-Fortes S, et al. Among authors: huebner k. Cancers (Basel). 2021 Dec 28;14(1):136. doi: 10.3390/cancers14010136. Cancers (Basel). 2021. PMID: 35008299 Free PMC article.
Tetraspanin 5 (TSPAN5), a Novel Gatekeeper of the Tumor Suppressor DLC1 and Myocardin-Related Transcription Factors (MRTFs), Controls HCC Growth and Senescence.
Schreyer L, Mittermeier C, Franz MJ, Meier MA, Martin DE, Maier KC, Huebner K, Schneider-Stock R, Singer S, Holzer K, Fischer D, Ribback S, Liebl B, Gudermann T, Aigner A, Muehlich S. Schreyer L, et al. Among authors: huebner k. Cancers (Basel). 2021 Oct 26;13(21):5373. doi: 10.3390/cancers13215373. Cancers (Basel). 2021. PMID: 34771537 Free PMC article.